Ttc3 - tetratricopeptide repeat domain 3 Gene

Also Known as TPRD; D16Ium21; D16Ium21e; mKIAA4119; 2610202A04Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 22129

Summary

Predicted to enable ubiquitin-protein transferase activity. Acts upstream of or within negative regulation of cell morphogenesis involved in differentiation and negative regulation of neuron differentiation. Located in vacuole. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human TTC3 (tetratricopeptide repeat domain 3). [provided by Alliance of Genome Resources, Apr 2022]

Ttc3 Products (1)

mRNA Protein Name
NM_009441.2 NP_033467.2 E3 ubiquitin-protein ligase TTC3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
17488780 MGI
Biological Process GO Annotation Evidence References Source
involved in negative regulation of axon extension IDA
IDA: Inferred from direct assay
17488780 MGI
involved in negative regulation of neuron differentiation IDA
IDA: Inferred from direct assay
17488780 MGI
Cellular Component GO Annotation Evidence References Source
located in vacuole IDA
IDA: Inferred from direct assay
17488780 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase TTC3

  • RING-type E3 ubiquitin transferase TTC3

  • TPR repeat protein D

  • mtprd

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15208 TTC3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ttc3 NCBI NCBI:7267