2. Gene
  3. Tulp1 - tubby like protein 1 Gene

Tulp1 - tubby like protein 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Tulp1l

Gene ID: 22157 | Gene type: protein coding

About Tulp1

Summary

Predicted to enable actin filament binding activity and phosphatidylinositol-4,5-bisphosphate binding activity. Involved in dendrite development; eye photoreceptor cell development; and photoreceptor cell maintenance. Acts upstream of or within phagocytosis, recognition; protein localization to photoreceptor outer segment; and retina development in camera-type eye. Located in several cellular components, including axon terminus; photoreceptor inner segment; and photoreceptor outer segment. Used to study retinitis pigmentosa 14. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 15; retinitis pigmentosa; and retinitis pigmentosa 14. Orthologous to human TULP1 (TUB like protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Tulp1 Products(1)

mRNA Protein Name
NM_021478.2 NP_067453.1 tubby-related protein 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
19837063 MGI
Biological Process GO Annotation Evidence Reference Source
involved in dendrite development IMP
IMP: Inferred from mutant phenotype
19218615 MGI
involved in eye photoreceptor cell development IMP
IMP: Inferred from mutant phenotype
19218615 MGI
acts upstream of or within phagocytosis, recognition IDA
IDA: Inferred from direct assay
20978472 MGI
acts upstream of or within phagocytosis, recognition IMP
IMP: Inferred from mutant phenotype
19837063 MGI
acts upstream of or within photoreceptor cell maintenance IMP
IMP: Inferred from mutant phenotype
10549638 MGI
involved in photoreceptor cell maintenance IMP
IMP: Inferred from mutant phenotype
19218615 MGI
acts upstream of or within protein localization to photoreceptor outer segment IMP
IMP: Inferred from mutant phenotype
11481257 MGI
acts upstream of or within retina development in camera-type eye IMP
IMP: Inferred from mutant phenotype
21052544 MGI
acts upstream of or within vesicle-mediated transport IMP
IMP: Inferred from mutant phenotype
10549638 MGI
Cellular Component GO Annotation Evidence Reference Source
located in axon terminus IDA
IDA: Inferred from direct assay
11481257 MGI
located in cytosol IDA
IDA: Inferred from direct assay
11481257 MGI
located in extracellular region IDA
IDA: Inferred from direct assay
19695251 MGI
located in photoreceptor inner segment IDA
IDA: Inferred from direct assay
10549638 MGI
located in photoreceptor outer segment IDA
IDA: Inferred from direct assay
19218615 MGI
located in synapse IDA
IDA: Inferred from direct assay
19218615 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tubby-related protein 1

tubby like protein 1 like

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15270 TULP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tulp1 NCBI NCBI:7287