ZSCAN25 - zinc finger and SCAN domain containing 25 Gene

Also Known as ZNF498

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 221785

About ZSCAN25

This gene has 10 transcripts (splice variants), 88 orthologues and 31 paralogues. Ubiquitous expression in small intestine (RPKM 5.1), duodenum (RPKM 3.7) and 25 other tissues.

Summary

This gene encodes a protein that bears some similarity to zinc finger proteins, which are involved in DNA binding and protein-protein interactions. Multiple alternatively spliced transcript variants have been identified, but the full-length nature for most of them has not been determined. [provided by RefSeq, Jul 2008]

ZSCAN25 Products (9)

mRNA Protein Name
NM_001350979.2 NP_001337908.1 zinc finger and SCAN domain-containing protein 25 isoform a
NM_001350980.2 NP_001337909.1 zinc finger and SCAN domain-containing protein 25 isoform a
NM_001350981.2 NP_001337910.1 zinc finger and SCAN domain-containing protein 25 isoform b
NM_001350982.2 NP_001337911.1 zinc finger and SCAN domain-containing protein 25 isoform b
NM_001350983.2 NP_001337912.1 zinc finger and SCAN domain-containing protein 25 isoform b
NM_001350984.2 NP_001337913.1 zinc finger and SCAN domain-containing protein 25 isoform c
NM_001350985.2 NP_001337914.1 zinc finger and SCAN domain-containing protein 25 isoform c
NM_001350986.2 NP_001337915.1 zinc finger and SCAN domain-containing protein 25 isoform d
NM_145115.3 NP_660090.2 zinc finger and SCAN domain-containing protein 25 isoform a

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZSCAN25 Protein Structure

SCAN

SCAN: SCAN domain (37 - 126)

zf-C2H2

zf-C2H2: Zinc finger, C2H2 type (348 - 370)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (390 - 413)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (417 - 441)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (445 - 468)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (472 - 496)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (501 - 524)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 544 a.a.
Protein Preferred Names Protein Names

zinc finger and SCAN domain-containing protein 25

  • zinc finger protein 498

Related Diseases

Diseases Alias
Hypertension, Essential

  • Essential Hypertension

  • Hypertension

  • High Blood Pressure

  • Hypertension, Essential, Susceptibility To

  • Hypertensive Disease

  • Primary Hypertension

  • EHT

  • Hypertension, Salt-Sensitive Essential, Susceptibility To

  • Hyperpiesia

  • Idiopathic Hypertension

  • Hypertensive Disorder

  • Hypertension, Essential, Susceptibility To, 3

  • Hypertension, Essential 3

  • Hypertension, Essential, Salt-Sensitive

  • Hypertension, Essential, Susceptibility To, 6

  • Hypertension, Essential 6

  • Hypertension, Salt-Sensitive Essential

  • Hypertension, Susceptibility To

  • Hypertension, Essential, Susceptibility To, 4

  • Hypertension, Essential 4

  • Hypertension, Essential, Susceptibility To, 2

  • Hypertension, Essential 2

  • Hypertension, Essential, Susceptibility To, 1

  • Hypertension, Essential 1

  • Hypertension, Essential, Susceptibility To, 5

  • Hypertension, Essential 5

  • Htn

  • Vascular Hypertensive Disorder

  • Systemic Primary Arterial Hypertension

  • Hbp - [High Blood Pressure]

  • Systemic Arterial Hypertensive Disorder

  • Elevated Blood Pressure

  • Arterial Hypertension Nos

  • Hypertension Nos

  • Benign Hypertension

  • Systemic Arterial Hypertension

  • Systemic Hypertension

  • Artery Htn

  • Benign Htn

  • Vascular Htn

  • Vascular Hypertension

  • Cholesterol Hypertension

  • Cholesterol Htn

  • Idiopathic Htn

  • Malignant Hypertension

  • Malignant Htn

  • Raised Blood Pressure

  • Cardiovascular Hypertension

  • Primary Htn - [Hypertension]

  • High Arterial Tension

  • High Blood Pressure Disorder

  • Ht - [Hypertension]

  • Htn - [Hypertension]

  • Hypertensive Vascular Disease

  • Hypertensive Vascular Degeneration
Avoidant Personality Disorder

  • Anxious Personality Disorder

  • Personality Disorders
Pituitary Adenoma 1, Multiple Types

  • Pituitary Adenoma Predisposition

  • PITA1

  • Isolated Familial Somatotropinoma

  • Fis

  • Ifs

  • Somatotrophinoma, Familial

  • Acromegaly Due To Pituitary Adenoma 1

  • Pagh1

  • Pituitary Adenoma 1

  • Somatotropinoma, Familial Isolated

  • Somatotropic Adenoma

  • Somatotropinoma

  • Pituitary Gigantism

  • Hypophyseal Gigantism

  • Infantile And Juvenile Forms Of Acromegaly

  • Acromegaly Due To Pituitary Adenoma

  • Familial Isolated Pituitary Adenoma

  • Familial Isolated Somatotropinomas

  • Familial Somatotrophinoma

  • Fipa

  • Pituitary Adenoma, Growth Hormone-Secreting, 1

  • Gigantism Pituitary

  • Pituitary Adenoma, Type 1, Multiple Types

  • Gigantism

  • Pituitary Adenoma, Familial Isolated

  • Multiple Gastrointestinal Atresias
Expressive Language Disorder

  • Developmental Expressive Language Disorder
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS16201 ZSCAN25 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus ZSCAN25 MGD MGI:3647079
Canis familiaris ZSCAN25 VGNC VGNC:48852
Macaca mulatta ZSCAN25 VGNC VGNC:79344
Rattus norvegicus ZSCAN25 RGD RGD:1308619
Others ZSCAN25 NCBI