Upk3a - uroplakin 3A Gene

Also Known as UP3a; Upk3; UPIII; 1110017C07Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 22270

Summary

Acts upstream of or within several processes, including monovalent inorganic cation homeostasis; urea transport; and urogenital system development. Located in apical plasma membrane urothelial plaque. Is expressed in several structures, including alimentary system; lung; male reproductive system; notochord; and urinary system. Used to study vesicoureteral reflux. Orthologous to human UPK3A (uroplakin 3A). [provided by Alliance of Genome Resources, Apr 2022]

Upk3a Products (1)

mRNA Protein Name
NM_023478.2 NP_075967.2 uroplakin-3a precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within cell morphogenesis IMP
IMP: Inferred from mutant phenotype
12388410 MGI
acts upstream of or within kidney development IMP
IMP: Inferred from mutant phenotype
12388410 MGI
acts upstream of or within potassium ion homeostasis IMP
IMP: Inferred from mutant phenotype
12388410 MGI
acts upstream of or within sodium ion homeostasis IMP
IMP: Inferred from mutant phenotype
12388410 MGI
acts upstream of or within urea transport IMP
IMP: Inferred from mutant phenotype
12388410 MGI
acts upstream of or within urinary bladder development IMP
IMP: Inferred from mutant phenotype
12388410 MGI
acts upstream of or within water transport IMP
IMP: Inferred from mutant phenotype
12388410 MGI
Cellular Component GO Annotation Evidence References Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
8175808 MGI
is active in apical plasma membrane urothelial plaque EXP
EXP: Inferred from Experiment
26046524 MGI
is active in apical plasma membrane urothelial plaque IDA
IDA: Inferred from direct assay
22323295 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

uroplakin-3a

  • proplakin IIIa

  • uroplakin 3

  • uroplakin III

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15488 UPK3A Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Upk3a NCBI NCBI:7380