Vpreb1a - V-set pre-B cell surrogate light chain 1A Gene

Also Known as CD179a; Vpreb1; Vpreb-1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 22362

Summary

Enables signaling receptor activity. Acts upstream of or within several processes, including B cell proliferation; homeostasis of number of cells; and regulation of cell size. Located in external side of plasma membrane. Is expressed in bone marrow; liver; and spleen. Orthologous to human VPREB1 (V-set pre-B cell surrogate light chain 1). [provided by Alliance of Genome Resources, Apr 2022]

Vpreb1a Products (1)

mRNA Protein Name
NM_016982.2 NP_058678.1 immunoglobulin iota chain precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
8625987 MGI
enables signaling receptor activity IPI
IPI: Inferred from physical interaction
8625987 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within B cell homeostasis IGI
IGI: Inferred from genetic interaction
15909309 MGI
acts upstream of or within B cell proliferation IGI
IGI: Inferred from genetic interaction
15909309 MGI
acts upstream of or within B cell proliferation IMP
IMP: Inferred from mutant phenotype
15909309 MGI
acts upstream of or within cell morphogenesis IGI
IGI: Inferred from genetic interaction
15909309 MGI
acts upstream of or within hemopoiesis IMP
IMP: Inferred from mutant phenotype
10221657 MGI
acts upstream of or within immune response IPI
IPI: Inferred from physical interaction
8625987 MGI
acts upstream of or within immunoglobulin production IGI
IGI: Inferred from genetic interaction
15909309 MGI
acts upstream of or within regulation of cell size IDA
IDA: Inferred from direct assay
15909309 MGI
acts upstream of or within regulation of cell size IGI
IGI: Inferred from genetic interaction
15909309 MGI
Cellular Component GO Annotation Evidence References Source
located in external side of plasma membrane IDA
IDA: Inferred from direct assay
15909309 MGI
located in plasma membrane IPI
IPI: Inferred from physical interaction
8625987 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

immunoglobulin iota chain

  • pre-B lymphocyte gene 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15669 VPREB1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown