Rapgef3 - Rap guanine nucleotide exchange factor (GEF) 3 Gene

Also Known as Epac; Epac1; 2310016P22Rik; 9330170P05Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 223864

Summary

Enables guanyl-nucleotide exchange factor activity. Involved in associative learning. Predicted to be located in several cellular components, including basolateral part of cell; brush border membrane; and distal axon. Predicted to colocalize with cortical actin Cytoskeleton and plasma membrane. Is expressed in brain; heart; lung; and metanephros. Orthologous to human RAPGEF3 (Rap guanine nucleotide exchange factor 3). [provided by Alliance of Genome Resources, Apr 2022]

Rapgef3 Products (4)

mRNA Protein Name
NM_001177810.1 NP_001171281.1 rap guanine nucleotide exchange factor 3 isoform 1
NM_001177811.1 NP_001171282.1 rap guanine nucleotide exchange factor 3 isoform 3
NM_001357630.1 NP_001344559.1 rap guanine nucleotide exchange factor 3 isoform 4
NM_144850.2 NP_659099.2 rap guanine nucleotide exchange factor 3 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables guanyl-nucleotide exchange factor activity IDA
IDA: Inferred from direct assay
14712229 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
23540699 MGI
Biological Process GO Annotation Evidence References Source
involved in associative learning IMP
IMP: Inferred from mutant phenotype
26158416 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

rap guanine nucleotide exchange factor 3

  • Rap1 guanine-nucleotide-exchange factor directly activated by cAMP

  • cAMP-GEFI

  • cAMP-regulated guanine nucleotide exchange factor I

  • exchange protein directly activated by cAMP 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11662 RAPGEF3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rapgef3 NCBI NCBI:10411