2. Gene
  3. Klhl22 - kelch-like 22 Gene

Klhl22 - kelch-like 22 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Kelchl; 2610318I18Rik

Gene ID: 224023 | Gene type: protein coding

About Klhl22

Summary

Predicted to enable 14-3-3 protein binding activity. Involved in cellular response to amino acid stimulus and positive regulation of TORC1 signaling. Predicted to be located in several cellular components, including cytosol; intercellular bridge; and microtubule Cytoskeleton. Predicted to be part of Cul3-RING ubiquitin Ligase complex. Predicted to be active in cytoplasm and microtubule Cytoskeleton. Predicted to colocalize with lysosome and nucleus. Orthologous to human KLHL22 (kelch like family member 22). [provided by Alliance of Genome Resources, Apr 2022]

Klhl22 Products(7)

mRNA Protein Name
NM_001359068.1 NP_001345997.1 kelch-like protein 22 isoform 1
NM_001379022.1 NP_001365951.1 kelch-like protein 22 isoform 1
NM_001379023.1 NP_001365952.1 kelch-like protein 22 isoform 1
NM_001379024.1 NP_001365953.1 kelch-like protein 22 isoform 2
NM_001379025.1 NP_001365954.1 kelch-like protein 22 isoform 3
NM_001379026.1 NP_001365955.1 kelch-like protein 22 isoform 3
NM_145479.4 NP_663454.3 kelch-like protein 22 isoform 1
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in cellular response to amino acid stimulus IMP
IMP: Inferred from mutant phenotype
29769719 MGI
involved in positive regulation of TORC1 signaling IMP
IMP: Inferred from mutant phenotype
29769719 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

kelch-like protein 22

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07363 KLHL22 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Klhl22 NCBI NCBI:84861