Klhl22 - kelch-like 22 Gene
Also Known as Kelchl; 2610318I18Rik
Species: Mus musculus
Gene Type: protein coding
Gene ID: 224023
Summary
Predicted to enable 14-3-3 protein binding activity. Involved in cellular response to amino acid stimulus and positive regulation of TORC1 signaling. Predicted to be located in several cellular components, including cytosol; intercellular bridge; and microtubule Cytoskeleton. Predicted to be part of Cul3-RING ubiquitin Ligase complex. Predicted to be active in cytoplasm and microtubule Cytoskeleton. Predicted to colocalize with lysosome and nucleus. Orthologous to human KLHL22 (kelch like family member 22). [provided by Alliance of Genome Resources, Apr 2022]
Klhl22 Products (7)
| mRNA | Protein | Name |
|---|---|---|
| NM_001359068.1 | NP_001345997.1 | kelch-like protein 22 isoform 1 |
| NM_001379022.1 | NP_001365951.1 | kelch-like protein 22 isoform 1 |
| NM_001379023.1 | NP_001365952.1 | kelch-like protein 22 isoform 1 |
| NM_001379024.1 | NP_001365953.1 | kelch-like protein 22 isoform 2 |
| NM_001379025.1 | NP_001365954.1 | kelch-like protein 22 isoform 3 |
| NM_001379026.1 | NP_001365955.1 | kelch-like protein 22 isoform 3 |
| NM_145479.4 | NP_663454.3 | kelch-like protein 22 isoform 1 |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in cellular response to amino acid stimulus |
IMP
IMP: Inferred from mutant phenotype
|
29769719 | MGI |
| involved in positive regulation of TORC1 signaling |
IMP
IMP: Inferred from mutant phenotype
|
29769719 | MGI |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
kelch-like protein 22 |
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
Bioactive Molecules
(1)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS07363 | KLHL22 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
Compound Screening Libraries
Virtual Screening
Customize Your Library
Drug Screening Service