Eif2b5 - eukaryotic translation initiation factor 2B, subunit 5 epsilon Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 224045

Summary

Predicted to enable guanyl-nucleotide exchange factor activity; translation initiation factor activity; and translation initiation factor binding activity. Predicted to be involved in several processes, including T cell receptor signaling pathway; glial cell development; and translational initiation. Predicted to act upstream of or within translation. Located in cytoplasm and nucleus. Is expressed in central nervous system and retina. Used to study leukoencephalopathy with vanishing white matter. Human ortholog(s) of this gene implicated in leukoencephalopathy with vanishing white matter. Orthologous to human EIF2B5 (eukaryotic translation initiation factor 2B subunit epsilon). [provided by Alliance of Genome Resources, Apr 2022]

Eif2b5 Products (1)

mRNA Protein Name
NM_172265.2 NP_758469.1 translation initiation factor eIF-2B subunit epsilon

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
12388085 MGI
located in nucleus IDA
IDA: Inferred from direct assay
12388085 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

translation initiation factor eIF-2B subunit epsilon

  • eIF-2B GDP-GTP exchange factor subunit epsilon

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04252 EIF2B5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Eif2b5 NCBI NCBI:8893