Wnt2b - wingless-type MMTV integration site family, member 2B Gene

Also Known as Wnt13

Species: Mus musculus

Gene Type: protein coding
Gene ID: 22414

Summary

Predicted to enable cytokine activity and Frizzled binding activity. Acts upstream of or within several processes, including forebrain regionalization; mesenchymal-epithelial cell signaling; and regulation of morphogenesis of a branching structure. Predicted to be located in intracellular membrane-bounded organelle. Predicted to be active in extracellular space. Is expressed in several structures, including alimentary system; brain; reproductive system; sensory organ; and urethra. Human ortholog(s) of this gene implicated in congenital diarrhea. Orthologous to human WNT2B (Wnt family member 2B). [provided by Alliance of Genome Resources, Apr 2022]

Wnt2b Products (1)

mRNA Protein Name
NM_009520.3 NP_033546.2 protein Wnt-2b

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
21856951 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within canonical Wnt signaling pathway IGI
IGI: Inferred from genetic interaction
19686689 MGI
acts upstream of or within cellular response to starvation IEP
IEP: Inferred from expression pattern
23260145 MGI
involved in forebrain regionalization IEP
IEP: Inferred from expression pattern
15164427 MGI
acts upstream of or within lung induction IGI
IGI: Inferred from genetic interaction
19686689 MGI
acts upstream of or within mesenchymal-epithelial cell signaling IDA
IDA: Inferred from direct assay
11507767 MGI
acts upstream of or within positive regulation of branching involved in ureteric bud morphogenesis IDA
IDA: Inferred from direct assay
11507767 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein Wnt-2b

  • wingless related MMTV integration site 2b

  • wnt-13

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15833 WNT2B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22922 Wnt2b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29436 Wnt2b Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Wnt2b NCBI NCBI:7482