Xirp1 - xin actin-binding repeat containing 1 Gene

Also Known as Cmya1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 22437

Summary

Predicted to enable actin filament binding activity and filamin binding activity. Acts upstream of or within several processes, including Notch signaling pathway; muscle cell development; and negative regulation of cell population proliferation. Located in adherens junction and fascia adherens. Is expressed in several structures, including heart; musculature; and tail somite. Used to study hypertrophic cardiomyopathy. Orthologous to human XIRP1 (xin actin binding repeat containing 1). [provided by Alliance of Genome Resources, Apr 2022]

Xirp1 Products (2)

mRNA Protein Name
NM_001406404.1 NP_001393333.1 xin actin-binding repeat-containing protein 1
NM_011724.5 NP_035854.4 xin actin-binding repeat-containing protein 1

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within Notch signaling pathway IDA
IDA: Inferred from direct assay
23117660 MGI
acts upstream of or within cardiac muscle cell development IMP
IMP: Inferred from mutant phenotype
17766470 MGI
involved in myoblast differentiation involved in skeletal muscle regeneration IMP
IMP: Inferred from mutant phenotype
25582411 MGI
acts upstream of or within negative regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
17855775 MGI
involved in protein localization IMP
IMP: Inferred from mutant phenotype
23296090 MGI
acts upstream of or within regulation of membrane potential IMP
IMP: Inferred from mutant phenotype
17766470 MGI
acts upstream of or within sarcomere organization IMP
IMP: Inferred from mutant phenotype
17766470 MGI
involved in satellite cell activation involved in skeletal muscle regeneration IMP
IMP: Inferred from mutant phenotype
25582411 MGI
Cellular Component GO Annotation Evidence References Source
located in adherens junction IDA
IDA: Inferred from direct assay
12203715 MGI
located in fascia adherens IDA
IDA: Inferred from direct assay
10021346 MGI
located in intercalated disc IDA
IDA: Inferred from direct assay
17766470 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

xin actin-binding repeat-containing protein 1

  • Xin alpha

  • cardiomyopathy associated 1

  • cardiomyopathy-associated protein 1

  • mXin alpha

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15876 XIRP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Xirp1 NCBI NCBI:165904