Tbc1d24 - TBC1 domain family, member 24 Gene

Predicted to enable GTPase activator activity. Acts upstream of or within several processes, including negative regulation of oxidative stress-induced neuron death; negative regulation of peptidyl-cysteine S-nitrosylation; and neuron projection development. Predicted to be located in cell junction and cytoplasm. Predicted to be active in neuromuscular junction and plasma membrane. Is expressed in several structures, including central nervous system; genitourinary system; olfactory epithelium; retina; and spleen. Used to study developmental and epileptic encephalopathy 16. Human ortholog(s) of this gene implicated in DOORS syndrome; epilepsy (multiple); and nonsyndromic deafness (multiple). Orthologous to human TBC1D24 (TBC1 domain family member 24). [provided by Alliance of Genome Resources, Apr 2022]