2. Gene
  3. Tbc1d24 - TBC1 domain family, member 24 Gene

Tbc1d24 - TBC1 domain family, member 24 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as mKIAA1171; 9630033P11; C530046L02Rik

Gene ID: 224617 | Gene type: protein coding

About Tbc1d24

Summary

Predicted to enable GTPase activator activity. Acts upstream of or within several processes, including negative regulation of oxidative stress-induced neuron death; negative regulation of peptidyl-cysteine S-nitrosylation; and neuron projection development. Predicted to be located in cell junction and cytoplasm. Predicted to be active in neuromuscular junction and plasma membrane. Is expressed in several structures, including central nervous system; genitourinary system; olfactory epithelium; retina; and spleen. Used to study developmental and epileptic encephalopathy 16. Human ortholog(s) of this gene implicated in DOORS syndrome; epilepsy (multiple); and nonsyndromic deafness (multiple). Orthologous to human TBC1D24 (TBC1 domain family member 24). [provided by Alliance of Genome Resources, Apr 2022]

Tbc1d24 Products(8)

mRNA Protein Name
NM_001163847.1 NP_001157319.1 TBC1 domain family member 24 isoform a
NM_001163848.1 NP_001157320.1 TBC1 domain family member 24 isoform a
NM_001163849.1 NP_001157321.1 TBC1 domain family member 24 isoform a
NM_001163850.1 NP_001157322.1 TBC1 domain family member 24 isoform b
NM_001163851.1 NP_001157323.1 TBC1 domain family member 24 isoform b
NM_001163852.1 NP_001157324.1 TBC1 domain family member 24 isoform b
NM_001163853.1 NP_001157325.1 TBC1 domain family member 24 isoform b
NM_173186.4 NP_775278.3 TBC1 domain family member 24 isoform b
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within axon development IMP
IMP: Inferred from mutant phenotype
30335140 MGI
acts upstream of or within cellular response to oxidative stress IMP
IMP: Inferred from mutant phenotype
30335140 MGI
acts upstream of or within dendrite development IMP
IMP: Inferred from mutant phenotype
30335140 MGI
acts upstream of or within negative regulation of cellular response to oxidative stress IDA
IDA: Inferred from direct assay
26668325 MGI
acts upstream of or within negative regulation of peptidyl-cysteine S-nitrosylation IDA
IDA: Inferred from direct assay
26668325 MGI
acts upstream of or within neuron projection development IMP
IMP: Inferred from mutant phenotype
30335140 MGI
acts upstream of or within synaptic vesicle endocytosis IMP
IMP: Inferred from mutant phenotype
30335140 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

TBC1 domain family member 24

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14238 TBC1D24 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tbc1d24 NCBI NCBI:57465