Vps52 - VPS52 GARP complex subunit Gene

Also Known as ARE1; SAC2; tclw5; Sacm2l; D130068D18; D430041K17Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 224705

Summary

Predicted to enable syntaxin binding activity. Acts upstream of or within ectodermal cell differentiation and embryonic ectodermal digestive tract development. Predicted to be located in several cellular components, including Golgi apparatus; perinuclear region of cytoplasm; and recycling endosome. Predicted to be part of EARP complex and GARP complex. Is expressed in several structures, including brain; genitourinary system; heart; hemolymphoid system gland; and liver. Orthologous to human VPS52 (VPS52 subunit of GARP complex). [provided by Alliance of Genome Resources, Apr 2022]

Vps52 Products (5)

mRNA Protein Name
NM_001357329.1 NP_001344258.1 vacuolar protein sorting-associated protein 52 homolog isoform 2
NM_001357330.1 NP_001344259.1 vacuolar protein sorting-associated protein 52 homolog isoform 3
NM_001379410.1 NP_001366339.1 vacuolar protein sorting-associated protein 52 homolog isoform 4
NM_001379411.1 NP_001366340.1 vacuolar protein sorting-associated protein 52 homolog isoform 5
NM_172620.4 NP_766208.2 vacuolar protein sorting-associated protein 52 homolog isoform 1

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within ectodermal cell differentiation IMP
IMP: Inferred from mutant phenotype
23142660 MGI
acts upstream of or within embryonic ectodermal digestive tract development IMP
IMP: Inferred from mutant phenotype
23142660 MGI
involved in protein targeting IMP
IMP: Inferred from mutant phenotype
28658628 MGI
involved in vesicle-mediated cholesterol transport IMP
IMP: Inferred from mutant phenotype
28658628 MGI
Cellular Component GO Annotation Evidence References Source
is active in postsynapse IDA
IDA: Inferred from direct assay
32473257 MGI
is active in presynapse IDA
IDA: Inferred from direct assay
32473257 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

vacuolar protein sorting-associated protein 52 homolog

  • vacuolar protein sorting 52

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15697 VPS52 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Vps52 NCBI NCBI:6293