Pex6 - peroxisomal biogenesis factor 6 Gene

Also Known as PAF-2; D130055I09Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 224824

Summary

Predicted to enable ATP binding activity; ATP hydrolysis activity; and protein C-terminus binding activity. Predicted to be involved in protein import into peroxisome matrix, translocation and protein stabilization. Located in photoreceptor cell cilium. Is expressed in brain; embryo; liver; and metanephros. Human ortholog(s) of this gene implicated in Heimler syndrome 2; peroxisomal biogenesis disorder; and peroxisome biogenesis disorder 4A. Orthologous to human PEX6 (peroxisomal biogenesis factor 6). [provided by Alliance of Genome Resources, Apr 2022]

Pex6 Products (1)

mRNA Protein Name
NM_145488.2 NP_663463.1 peroxisome assembly factor 2

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
14651998 MGI
Cellular Component GO Annotation Evidence References Source
located in photoreceptor cell cilium IDA
IDA: Inferred from direct assay
26593283 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

peroxisome assembly factor 2

  • peroxin-6

  • peroxisomal-type ATPase 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10353 PEX6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pex6 NCBI NCBI:5190