Crb3 - crumbs family member 3 Gene

Also Known as 5730439B18

Species: Mus musculus

Gene Type: protein coding
Gene ID: 224912

Summary

Predicted to enable SH3 domain binding activity. Involved in positive regulation of cell junction assembly. Located in apical part of cell. Part of subapical complex. Is expressed in several structures, including central nervous system; early conceptus; and retina. Orthologous to human CRB3 (crumbs cell polarity complex component 3). [provided by Alliance of Genome Resources, Apr 2022]

Crb3 Products (4)

mRNA Protein Name
NM_001347408.1 NP_001334337.1 protein crumbs homolog 3 isoform 2
NM_001359813.1 NP_001346742.1 protein crumbs homolog 3 isoform 1 precursor
NM_001359814.1 NP_001346743.1 protein crumbs homolog 3 isoform 2
NM_177638.5 NP_808306.1 protein crumbs homolog 3 isoform 1 precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in positive regulation of cell junction assembly IMP
IMP: Inferred from mutant phenotype
21145499 MGI
Cellular Component GO Annotation Evidence References Source
located in apical part of cell IDA
IDA: Inferred from direct assay
24191021 MGI
part of subapical complex IDA
IDA: Inferred from direct assay
16885194 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein crumbs homolog 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03142 CRB3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Crb3 NCBI NCBI:92359