Ndufs8 - NADH:ubiquinone oxidoreductase core subunit S8 Gene
Also Known as TYKY; CI-23kD
Species: Mus musculus
Summary
Predicted to enable NADH dehydrogenase (ubiquinone) activity. Predicted to contribute to NADH dehydrogenase activity. Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone; mitochondrial respiratory chain complex I assembly; and response to oxidative stress. Located in mitochondrion. Part of mitochondrial respiratory chain complex I. Is expressed in several structures, including early conceptus and oocyte. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 2. Orthologous to human NDUFS8 (NADH:ubiquinone oxidoreductase core subunit S8). [provided by Alliance of Genome Resources, Apr 2022]
Ndufs8 Products (3)
| mRNA | Protein | Name |
|---|---|---|
| NM_001271443.1 | NP_001258372.1 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial |
| NM_001271444.1 | NP_001258373.1 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial |
| NM_144870.5 | NP_659119.2 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
31536960 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| part of respiratory chain complex I |
IDA
IDA: Inferred from direct assay
|
31536960 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial |
|
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS09164 | NDUFS8 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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