2. Gene
  3. Ndufs8 - NADH:ubiquinone oxidoreductase core subunit S8 Gene

Ndufs8 - NADH:ubiquinone oxidoreductase core subunit S8 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as TYKY; CI-23kD

Gene ID: 225887 | Gene type: protein coding

About Ndufs8

Summary

Predicted to enable NADH dehydrogenase (ubiquinone) activity. Predicted to contribute to NADH dehydrogenase activity. Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone; mitochondrial respiratory chain complex I assembly; and response to oxidative stress. Located in mitochondrion. Part of mitochondrial respiratory chain complex I. Is expressed in several structures, including early conceptus and oocyte. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 2. Orthologous to human NDUFS8 (NADH:ubiquinone oxidoreductase core subunit S8). [provided by Alliance of Genome Resources, Apr 2022]

Ndufs8 Products(3)

mRNA Protein Name
NM_001271443.1 NP_001258372.1 NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial
NM_001271444.1 NP_001258373.1 NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial
NM_144870.5 NP_659119.2 NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
31536960 MGI
Cellular Component GO Annotation Evidence Reference Source
part of respiratory chain complex I IDA
IDA: Inferred from direct assay
31536960 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial

NADH dehydrogenase (ubiquinone) Fe-S protein 8

NADH-ubiquinone oxidoreductase 23 kDa subunit

complex I-23kD

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09164 NDUFS8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ndufs8 NCBI NCBI:4728