Rab7b - RAB7B, member RAS oncogene family Gene

Also Known as 5430435G22Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 226421

Summary

Predicted to enable GTP binding activity and GTPase activity. Involved in negative regulation of Toll-like Receptor 4 signaling pathway and negative regulation of Toll-like Receptor 9 signaling pathway. Acts upstream of or within cellular response to interferon-gamma. Located in late endosome; lysosome; and phagocytic vesicle. Orthologous to human RAB7B (RAB7B, member Ras oncogene family). [provided by Alliance of Genome Resources, Apr 2022]

Rab7b Products (2)

mRNA Protein Name
NM_001311096.1 NP_001298025.1 ras-related protein Rab-7b isoform 2
NM_145509.3 NP_663484.1 ras-related protein Rab-7b isoform 1

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within cellular response to type II interferon IDA
IDA: Inferred from direct assay
19144319 MGI
involved in negative regulation of toll-like receptor 4 signaling pathway IMP
IMP: Inferred from mutant phenotype
17395780 MGI
involved in negative regulation of toll-like receptor 9 signaling pathway IMP
IMP: Inferred from mutant phenotype
19587007 MGI
Cellular Component GO Annotation Evidence References Source
located in late endosome IDA
IDA: Inferred from direct assay
17395780 MGI
located in lysosome IDA
IDA: Inferred from direct assay
17395780 MGI
located in phagocytic vesicle IDA
IDA: Inferred from direct assay
19144319 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ras-related protein Rab-7b

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11577 RAB7B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rab7b NCBI NCBI:338382