Zfp281 - zinc finger protein 281 Gene

Also Known as Znf281

Species: Mus musculus

Gene Type: protein coding
Gene ID: 226442

Summary

Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in embryonic body morphogenesis and stem cell differentiation. Predicted to be located in nucleoplasm. Is expressed in several structures, including branchial arch; extraembryonic component; forelimb bud; genitourinary system; and limb. Orthologous to human ZNF281 (Zinc Finger Protein 281). [provided by Alliance of Genome Resources, Apr 2022]

Zfp281 Products (2)

mRNA Protein Name
NM_001160251.1 NP_001153723.1 zinc finger protein 281
NM_177643.4 NP_808311.1 zinc finger protein 281

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription factor activity IMP
IMP: Inferred from mutant phenotype
21915945 MGI
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IMP
IMP: Inferred from mutant phenotype
21915945 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
22988117 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
17093407 MGI
Biological Process GO Annotation Evidence References Source
involved in embryonic body morphogenesis IMP
IMP: Inferred from mutant phenotype
21915945 MGI
involved in stem cell differentiation IMP
IMP: Inferred from mutant phenotype
21915945 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

zinc finger protein 281