2. Gene
  3. Zbtb14 - zinc finger and BTB domain containing 14 Gene

Zbtb14 - zinc finger and BTB domain containing 14 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as ZF5; Zfp161; b2b1982Clo

Gene ID: 22666 | Gene type: protein coding

About Zbtb14

Summary

Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Acts upstream of or within heart development and kidney development. Predicted to be located in aggresome; cytosol; and nucleolus. Predicted to be active in nucleoplasm. Is expressed in ureter. Orthologous to human ZBTB14 (zinc finger and BTB domain containing 14). [provided by Alliance of Genome Resources, Apr 2022]

Zbtb14 Products(3)

mRNA Protein Name
NM_001356282.1 NP_001343211.1 zinc finger and BTB domain-containing protein 14
NM_001356283.1 NP_001343212.1 zinc finger and BTB domain-containing protein 14
NM_009547.3 NP_033573.1 zinc finger and BTB domain-containing protein 14
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
8367294 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
8367294 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within cardiac septum development IMP
IMP: Inferred from mutant phenotype
25807483 MGI
acts upstream of or within coronary vasculature development IMP
IMP: Inferred from mutant phenotype
25807483 MGI
acts upstream of or within heart valve development IMP
IMP: Inferred from mutant phenotype
25807483 MGI
acts upstream of or within kidney development IMP
IMP: Inferred from mutant phenotype
27002738 MGI
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
8367294 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

zinc finger and BTB domain-containing protein 14

zfp-161

zinc finger protein 161

zinc finger protein 5

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15963 ZBTB14 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Zbtb14 NCBI NCBI:7541