Vash2 - vasohibin 2 Gene

Also Known as B130052G07Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 226841

Summary

Enables actin binding activity and metallocarboxypeptidase activity. Involved in proteolysis. Acts upstream of or within labyrinthine layer blood vessel development; positive regulation of angiogenesis; and syncytium formation by plasma membrane fusion. Predicted to be located in Cytoskeleton and extracellular region. Predicted to be active in cytoplasm. Is expressed in brain and hippocampus. Orthologous to human VASH2 (vasohibin 2). [provided by Alliance of Genome Resources, Apr 2022]

Vash2 Products (1)

mRNA Protein Name
NM_144879.2 NP_659128.2 tubulinyl-Tyr carboxypeptidase 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables actin binding IDA
IDA: Inferred from direct assay
29146868 MGI
enables metallocarboxypeptidase activity IDA
IDA: Inferred from direct assay
29146868 MGI
enables metallocarboxypeptidase activity IMP
IMP: Inferred from mutant phenotype
31324789 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
29146868 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within labyrinthine layer blood vessel development IMP
IMP: Inferred from mutant phenotype
25184477 MGI
acts upstream of or within labyrinthine layer development IMP
IMP: Inferred from mutant phenotype
25184477 MGI
acts upstream of or within placenta blood vessel development IMP
IMP: Inferred from mutant phenotype
25184477 MGI
acts upstream of or within positive regulation of angiogenesis IMP
IMP: Inferred from mutant phenotype
19204325 MGI
involved in proteolysis IDA
IDA: Inferred from direct assay
29146868 MGI
acts upstream of or within syncytium formation by plasma membrane fusion IMP
IMP: Inferred from mutant phenotype
25184477 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tubulinyl-Tyr carboxypeptidase 2

  • vasohibin-like protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15607 VASH2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22911 Vash2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29425 Vash2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Vash2 NCBI NCBI:79805