Flvcr1 - feline leukemia virus subgroup C cellular receptor 1 Gene

Also Known as FLVCR; Mfsd7b; 9630055N22Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 226844

Summary

Predicted to enable heme binding activity and heme transmembrane transporter activity. Acts upstream of or within several processes, including chordate embryonic development; embryonic digit morphogenesis; and hematopoietic or lymphoid organ development. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be active in mitochondrion. Is expressed in ectoplacental cone; immune system; liver; placenta; and yolk sac. Used to study Diamond-Blackfan anemia. Orthologous to human FLVCR1 (FLVCR heme transporter 1). [provided by Alliance of Genome Resources, Apr 2022]

Flvcr1 Products (3)

mRNA Protein Name
NM_001081259.1 NP_001074728.1 feline leukemia virus subgroup C receptor-related protein 1 isoform 1
NM_001313747.1 NP_001300676.1 feline leukemia virus subgroup C receptor-related protein 1 isoform 2
NM_198025.2 NP_932142.2 feline leukemia virus subgroup C receptor-related protein 1 isoform 3

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within blood vessel development IMP
IMP: Inferred from mutant phenotype
23187127 MGI
acts upstream of or within embryonic digit morphogenesis IMP
IMP: Inferred from mutant phenotype
18258918 MGI
acts upstream of or within embryonic skeletal system morphogenesis IMP
IMP: Inferred from mutant phenotype
23187127 MGI
acts upstream of or within erythrocyte differentiation IMP
IMP: Inferred from mutant phenotype
18258918 MGI
acts upstream of or within head morphogenesis IMP
IMP: Inferred from mutant phenotype
18258918 MGI
acts upstream of or within in utero embryonic development IMP
IMP: Inferred from mutant phenotype
18258918 MGI
acts upstream of or within limb morphogenesis IMP
IMP: Inferred from mutant phenotype
18258918 MGI
acts upstream of or within multicellular organism growth IMP
IMP: Inferred from mutant phenotype
18258918 MGI
acts upstream of or within regulation of organ growth IMP
IMP: Inferred from mutant phenotype
18258918 MGI
acts upstream of or within spleen development IMP
IMP: Inferred from mutant phenotype
18258918 MGI
Cellular Component GO Annotation Evidence References Source
located in mitochondrial membrane IDA
IDA: Inferred from direct assay
23187127 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
23187127 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

feline leukemia virus subgroup C receptor-related protein 1

  • major facilitator superfamily domain containing 7B

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04997 FLVCR1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21131 Flvcr1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27649 Flvcr1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Flvcr1 NCBI NCBI:28982