Zpr1 - ZPR1 zinc finger Gene

Also Known as Zfp259; Znf259

Species: Mus musculus

Gene Type: protein coding

Gene ID: 22687

Summary

Enables receptor tyrosine kinase binding activity; translation initiation factor binding activity; and zinc ion binding activity. Involved in several processes, including Cajal body organization; blastocyst growth; and nervous system development. Located in several cellular components, including growth cone; nuclear body; and perikaryon. Is expressed in several structures, including liver; lung; spleen; testis; and urinary system. Orthologous to human ZPR1 (ZPR1 zinc finger). [provided by Alliance of Genome Resources, Apr 2022]

Zpr1 Products (1)

mRNA	Protein	Name
NM_011752.2	NP_035882.1	zinc finger protein ZPR1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables protein binding	IPI IPI: Inferred from physical interaction	8650580	MGI
enables receptor tyrosine kinase binding	IPI IPI: Inferred from physical interaction	9852145	MGI
enables translation initiation factor binding	IPI IPI: Inferred from physical interaction	9852145	MGI
enables zinc ion binding	IDA IDA: Inferred from direct assay	8650580	MGI

Biological Process GO Annotation	Evidence	References	Source
involved in Cajal body organization	IMP IMP: Inferred from mutant phenotype	15767679	MGI
involved in DNA endoreduplication	IMP IMP: Inferred from mutant phenotype	15767679	MGI
involved in apoptotic process involved in development	IMP IMP: Inferred from mutant phenotype	15767679	MGI
involved in axon development	IMP IMP: Inferred from mutant phenotype	15767679	MGI
involved in inner cell mass cell proliferation	IMP IMP: Inferred from mutant phenotype	15767679	MGI
involved in microtubule cytoskeleton organization	IMP IMP: Inferred from mutant phenotype	16648254	MGI
involved in negative regulation of motor neuron apoptotic process	IMP IMP: Inferred from mutant phenotype	15767679	MGI
involved in positive regulation of gene expression	IMP IMP: Inferred from mutant phenotype	22422766	MGI
involved in positive regulation of growth	IMP IMP: Inferred from mutant phenotype	22422766	MGI
involved in positive regulation of protein import into nucleus	IMP IMP: Inferred from mutant phenotype	15767679	MGI
involved in regulation of myelination	IMP IMP: Inferred from mutant phenotype	22422766	MGI
involved in spinal cord development	IMP IMP: Inferred from mutant phenotype	22422766	MGI
involved in trophectodermal cell proliferation	IMP IMP: Inferred from mutant phenotype	15767679	MGI

Cellular Component GO Annotation	Evidence	References	Source
located in Cajal body	IDA IDA: Inferred from direct assay	15767679	MGI
located in Gemini of coiled bodies	IDA IDA: Inferred from direct assay	15767679	MGI
located in axon	IDA IDA: Inferred from direct assay	22422766	MGI
located in cytoplasm	IDA IDA: Inferred from direct assay	8650580	MGI
located in growth cone	IDA IDA: Inferred from direct assay	15767679	MGI
located in neuronal cell body	IDA IDA: Inferred from direct assay	15767679	MGI
located in nucleus	IDA IDA: Inferred from direct assay	8650580	MGI
located in perikaryon	IDA IDA: Inferred from direct assay	22422766	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names	Protein Names
zinc finger protein ZPR1	zinc finger protein 259

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS16192	ZPR1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Zpr1	NCBI	NCBI:8882