1. Gene
  2. Slc9a2 - solute carrier family 9 (sodium/hydrogen exchanger), member 2 Gene

Slc9a2 - solute carrier family 9 (sodium/hydrogen exchanger), member 2 Gene

Mus musculus

Also known as NHE2; 2210416H12Rik; 4932415O19Rik

Gene ID: 226999 | Gene type: protein coding

About Slc9a2

Summary

Enables sodium:proton antiporter activity. Acts upstream of or within protein localization; regulation of pH; and sodium ion transport. Predicted to be located in brush border. Predicted to be active in plasma membrane. Is expressed in genitourinary system and skeleton. Orthologous to human SLC9A2 (solute carrier family 9 member A2). [provided by Alliance of Genome Resources, Apr 2022]

Slc9a2 Products(1)

mRNA Protein Name
NM_001033289.2 NP_001028461.2 sodium/hydrogen exchanger 2 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables sodium:proton antiporter activity IDA
IDA: Inferred from direct assay
10666043 MGI
Biological Process GO Annotation Evidence Reference Source
involved in epithelial cell differentiation IMP
IMP: Inferred from mutant phenotype
34985202 MGI
acts upstream of or within protein localization IMP
IMP: Inferred from mutant phenotype
15800055 MGI
involved in regulation of intracellular pH IMP
IMP: Inferred from mutant phenotype
34985202 MGI
acts upstream of or within regulation of pH IDA
IDA: Inferred from direct assay
10666043 MGI
acts upstream of or within sodium ion transport IDA
IDA: Inferred from direct assay
10666043 MGI
Cellular Component GO Annotation Evidence Reference Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
21900251 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sodium/hydrogen exchanger 2

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc9a2 NCBI NCBI:6549