Slc39a10 - solute carrier family 39 (zinc transporter), member 10 Gene
Also Known as Zip10; mKIAA1265; 5430433I10; 2900042E17Rik
Species: Mus musculus
Summary
Enables zinc ion transmembrane transporter activity. Acts upstream of or within several processes, including positive regulation of B cell proliferation; positive regulation of B cell receptor signaling pathway; and positive regulation of protein tyrosine Phosphatase activity. Located in plasma membrane. Is expressed in several structures, including alimentary system; brain; ovary; sensory organ; and urinary system. Orthologous to human SLC39A10 (solute carrier family 39 member 10). [provided by Alliance of Genome Resources, Apr 2022]
Slc39a10 Products (3)
| mRNA | Protein | Name |
|---|---|---|
| NM_001356416.1 | NP_001343345.1 | zinc transporter ZIP10 precursor |
| NM_001356417.1 | NP_001343346.1 | zinc transporter ZIP10 precursor |
| NM_172653.3 | NP_766241.2 | zinc transporter ZIP10 precursor |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
27274087 | MGI |
| enables protein tyrosine phosphatase activator activity |
IMP
IMP: Inferred from mutant phenotype
|
25074919 | MGI |
| enables zinc ion transmembrane transporter activity |
IMP
IMP: Inferred from mutant phenotype
|
25074919 | MGI |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in epithelial to mesenchymal transition |
IDA
IDA: Inferred from direct assay
|
28098160 | MGI |
| acts upstream of or within intracellular zinc ion homeostasis |
IMP
IMP: Inferred from mutant phenotype
|
25074913 | MGI |
| acts upstream of or within negative regulation of B cell apoptotic process |
IMP
IMP: Inferred from mutant phenotype
|
25074913 | MGI |
| acts upstream of or within positive regulation of B cell proliferation |
IMP
IMP: Inferred from mutant phenotype
|
25074919 | MGI |
| acts upstream of or within positive regulation of B cell receptor signaling pathway |
IMP
IMP: Inferred from mutant phenotype
|
25074919 | MGI |
| acts upstream of or within zinc ion import across plasma membrane |
IMP
IMP: Inferred from mutant phenotype
|
25074913 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in apical plasma membrane |
IDA
IDA: Inferred from direct assay
|
30520657 | MGI |
| located in plasma membrane |
IDA
IDA: Inferred from direct assay
|
25074919 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
zinc transporter ZIP10 |
|
|