Ppip5k2 - diphosphoinositol pentakisphosphate kinase 2 Gene

Also Known as Vip2; Cfap160; Hisppd1; mKIAA0433; D330021B20

Species: Mus musculus

Gene Type: protein coding
Gene ID: 227399

Summary

Enables diphosphoinositol-pentakisphosphate kinase activity and inositol hexakisphosphate kinase activity. Predicted to be involved in inositol metabolic process and inositol phosphate biosynthetic process. Predicted to act upstream of or within sensory perception of sound. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; sensory organ; and skin. Used to study nonsyndromic deafness. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 100. Orthologous to human PPIP5K2 (diphosphoinositol pentakisphosphate kinase 2). [provided by Alliance of Genome Resources, Apr 2022]

Ppip5k2 Products (17)

mRNA Protein Name
NM_001405458.1 NP_001392387.1 inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform 1
NM_001405459.1 NP_001392388.1 inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform 2
NM_001405460.1 NP_001392389.1 inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform 2
NM_001405461.1 NP_001392390.1 inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform 3
NM_001405462.1 NP_001392391.1 inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform 4
NM_001405463.1 NP_001392392.1 inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform 5
NM_001405464.1 NP_001392393.1 inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform 6
NM_001405465.1 NP_001392394.1 inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform 7
NM_001405466.1 NP_001392395.1 inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform 8
NM_001405467.1 NP_001392396.1 inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform 9
NM_001405468.1 NP_001392397.1 inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform 10
NM_001405469.1 NP_001392398.1 inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform 11
NM_001405470.1 NP_001392399.1 inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform 13
NM_001405471.1 NP_001392400.1 inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform 14
NM_001405472.1 NP_001392401.1 inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform 15
NM_001405473.1 NP_001392402.1 inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform 16
NM_173760.6 NP_776121.4 inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform 12

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables 5-diphosphoinositol pentakisphosphate 1-kinase activity IDA
IDA: Inferred from direct assay
17690096 MGI
enables inositol hexakisphosphate kinase activity IDA
IDA: Inferred from direct assay
17690096 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2

  • VIP1 homolog 2

  • histidine acid phosphatase domain containing 1

  • histidine acid phosphatase domain-containing protein 1

  • insP6 and PP-IP5 kinase 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10958 PPIP5K2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ppip5k2 NCBI NCBI:23262