2. Gene
  3. Nup214 - nucleoporin 214 Gene

Nup214 - nucleoporin 214 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as CAN; D2H9S46E

Gene ID: 227720 | Gene type: protein coding

About Nup214

Summary

A structural constituent of nuclear pore. Acts upstream of or within mRNA export from nucleus; protein import into nucleus; and regulation of cell cycle. Predicted to be located in cytoplasmic side of nuclear pore. Predicted to be part of nuclear pore. Is expressed in future spinal cord; lung; and nervous system. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia; acute myeloid leukemia; and brain disease. Orthologous to human NUP214 (nucleoporin 214). [provided by Alliance of Genome Resources, Apr 2022]

Nup214 Products(2)

mRNA Protein Name
NM_001408097.1 NP_001395026.1 nuclear pore complex protein Nup214 isoform 2
NM_172268.3 NP_758472.2 nuclear pore complex protein Nup214 isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables structural constituent of nuclear pore IMP
IMP: Inferred from mutant phenotype
8896451 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within mRNA export from nucleus IMP
IMP: Inferred from mutant phenotype
8896451 MGI
acts upstream of or within protein import into nucleus IMP
IMP: Inferred from mutant phenotype
8896451 MGI
acts upstream of or within regulation of cell cycle IMP
IMP: Inferred from mutant phenotype
8896451 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nuclear pore complex protein Nup214

214 kDa nucleoporin

nucleoporin Nup214

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09692 NUP214 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nup214 NCBI NCBI:8021