2. Gene
  3. Cerkl - ceramide kinase-like Gene

Cerkl - ceramide kinase-like Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Rp26; Gm1958

Gene ID: 228094 | Gene type: protein coding

About Cerkl

Summary

Enables sphingolipid binding activity. Acts upstream of or within sphingolipid biosynthetic process. Located in several cellular components, including perinuclear region of cytoplasm; photoreceptor inner segment; and photoreceptor outer segment. Is expressed in eye and optic nerve. Used to study retinitis pigmentosa 26. Human ortholog(s) of this gene implicated in retinitis pigmentosa and retinitis pigmentosa 26. Orthologous to human CERKL (ceramide kinase like). [provided by Alliance of Genome Resources, Apr 2022]

Cerkl Products(2)

mRNA Protein Name
NM_001048176.1 NP_001041641.1 ceramide kinase-like protein
NM_001048176.1 NP_001041641.1 ceramide kinase-like protein
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
NOT enables ceramide kinase activity IDA
IDA: Inferred from direct assay
23501591 MGI
NOT enables ceramide kinase activity IMP
IMP: Inferred from mutant phenotype
18555012 MGI
enables sphingolipid binding IDA
IDA: Inferred from direct assay
23501591 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within sphingolipid biosynthetic process IMP
IMP: Inferred from mutant phenotype
23501591 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
21151604 MGI
located in nucleus IDA
IDA: Inferred from direct assay
21151604 MGI
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
21151604 MGI
located in photoreceptor inner segment IDA
IDA: Inferred from direct assay
23142158 MGI
located in photoreceptor outer segment IDA
IDA: Inferred from direct assay
23142158 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ceramide kinase-like protein

retinitis pigmentosa 26 (autosomal recessive)

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02535 CERKL Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cerkl NCBI NCBI:375298