NLGN4Y - neuroligin 4 Y-linked Gene

Also Known as HNL4Y

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 22829

About NLGN4Y

Cytogenetic location: Yq11.221 Genomic coordinates (GRCh38): Y:14,522,616-14,845,654 (from NCBI)

This gene has 11 transcripts (splice variants), 253 orthologues and 13 paralogues. Biased expression in brain (RPKM 2.6), prostate (RPKM 1.8) and 13 other tissues.

Summary

This gene encodes a type I membrane protein that belongs to the family of neuroligins, which are cell adhesion molecules present at the postsynaptic side of the synapse, and may be essential for the formation of functional synapses. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Mar 2011]

NLGN4Y Products (12)

mRNA Protein Name
NM_001164238.1 NP_001157710.1 neuroligin-4, Y-linked isoform 2 precursor
NM_001206850.2 NP_001193779.1 neuroligin-4, Y-linked isoform 3
NM_001365584.1 NP_001352513.1 neuroligin-4, Y-linked isoform 4
NM_001365586.1 NP_001352515.1 neuroligin-4, Y-linked isoform 4
NM_001365588.1 NP_001352517.1 neuroligin-4, Y-linked isoform 4
NM_001365590.1 NP_001352519.1 neuroligin-4, Y-linked isoform 1 precursor
NM_001365591.1 NP_001352520.1 neuroligin-4, Y-linked isoform 1 precursor
NM_001365592.1 NP_001352521.1 neuroligin-4, Y-linked isoform 1 precursor
NM_001365593.1 NP_001352522.1 neuroligin-4, Y-linked isoform 1 precursor
NM_001394830.1 NP_001381759.1 neuroligin-4, Y-linked isoform 4
NM_001394831.1 NP_001381760.1 neuroligin-4, Y-linked isoform 1 precursor
NM_014893.5 NP_055708.3 neuroligin-4, Y-linked isoform 1 precursor

NLGN4Y Protein Structure

COesterase

COesterase: Carboxylesterase family (30 - 590)

  • 0
  • 200
  • 400
  • 600
  • 816 a.a.
Protein Preferred Names Protein Names

neuroligin-4, Y-linked

  • alternative HNL4Y

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09343 NLGN4Y Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus NLGN4Y MGD MGI:3775191
Others NLGN4Y NCBI