2. Gene
  3. Arhgap1 - Rho GTPase activating protein 1 Gene

Arhgap1 - Rho GTPase activating protein 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Cdc42GAP; p50rhoGAP; B230365D05Rik

Gene ID: 228359 | Gene type: protein coding

About Arhgap1

Summary

Enables GTPase activator activity. Acts upstream of or within regulation of GTPase activity. Located in plasma membrane and ruffle. Orthologous to human ARHGAP1 (Rho GTPase activating protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Arhgap1 Products(3)

mRNA Protein Name
NM_001145902.1 NP_001139374.1 rho GTPase-activating protein 1 isoform 1
NM_001359970.1 NP_001346899.1 rho GTPase-activating protein 1 isoform 2
NM_146124.4 NP_666236.3 rho GTPase-activating protein 1 isoform 2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables GTPase activator activity IDA
IDA: Inferred from direct assay
10699171 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
18331715 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within regulation of GTPase activity IDA
IDA: Inferred from direct assay
10699171 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cell leading edge IDA
IDA: Inferred from direct assay
18331715 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
15860730 MGI
located in ruffle IDA
IDA: Inferred from direct assay
15860730 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

rho GTPase-activating protein 1

rho-type GTPase-activating protein 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00911 ARHGAP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Arhgap1 NCBI NCBI:392