Arhgap1 - Rho GTPase activating protein 1 Gene

Also Known as Cdc42GAP; p50rhoGAP; B230365D05Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 228359

Summary

Enables GTPase activator activity. Acts upstream of or within regulation of GTPase activity. Located in plasma membrane and ruffle. Orthologous to human ARHGAP1 (Rho GTPase activating protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Arhgap1 Products (3)

mRNA Protein Name
NM_001145902.1 NP_001139374.1 rho GTPase-activating protein 1 isoform 1
NM_001359970.1 NP_001346899.1 rho GTPase-activating protein 1 isoform 2
NM_146124.4 NP_666236.3 rho GTPase-activating protein 1 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables GTPase activator activity IDA
IDA: Inferred from direct assay
10699171 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
18331715 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within regulation of GTPase activity IDA
IDA: Inferred from direct assay
10699171 MGI
Cellular Component GO Annotation Evidence References Source
located in cell leading edge IDA
IDA: Inferred from direct assay
18331715 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
15860730 MGI
located in ruffle IDA
IDA: Inferred from direct assay
15860730 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

rho GTPase-activating protein 1

  • rho-type GTPase-activating protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00911 ARHGAP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Arhgap1 NCBI NCBI:392