2. Gene
  3. Slc35c1 - solute carrier family 35, member C1 Gene

Slc35c1 - solute carrier family 35, member C1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as fuct1; E430007K15Rik

Gene ID: 228368 | Gene type: protein coding

About Slc35c1

Summary

Predicted to enable GDP-fucose transmembrane transporter activity and antiporter activity. Acts upstream of or within lipid glycosylation and negative regulation of Notch signaling pathway. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in Golgi apparatus. Is expressed in several structures, including alimentary system; forelimb bud; integumental system; respiratory system; and telencephalon. Used to study congenital disorder of glycosylation type IIc. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIc. Orthologous to human SLC35C1 (solute carrier family 35 member C1). [provided by Alliance of Genome Resources, Apr 2022]

Slc35c1 Products(2)

mRNA Protein Name
NM_145832.3 NP_665831.1 GDP-fucose transporter 1 isoform 2
NM_211358.2 NP_997597.1 GDP-fucose transporter 1 isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables GDP-fucose transmembrane transporter activity IMP
IMP: Inferred from mutant phenotype
17276979 MGI
Biological Process GO Annotation Evidence Reference Source
involved in 'de novo' GDP-L-fucose biosynthetic process IMP
IMP: Inferred from mutant phenotype
17276979 MGI
involved in GDP-L-fucose salvage IMP
IMP: Inferred from mutant phenotype
17276979 MGI
acts upstream of or within lipid glycosylation IMP
IMP: Inferred from mutant phenotype
18308723 MGI
acts upstream of or within negative regulation of Notch signaling pathway IMP
IMP: Inferred from mutant phenotype
20837470 MGI
Cellular Component GO Annotation Evidence Reference Source
is active in Golgi membrane IMP
IMP: Inferred from mutant phenotype
17276979 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

GDP-fucose transporter 1

multispan transmembrane protein fuct1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13200 SLC35C1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc35c1 NCBI NCBI:55343