Ebf4 - early B cell factor 4 Gene

Also Known as Ebf3; O/E-4; Olf-1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 228598

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within regulation of transcription, DNA-templated. Predicted to be located in nucleus. Is expressed in several structures, including genitourinary system; nervous system; and retina. Orthologous to human EBF4 (EBF family member 4). [provided by Alliance of Genome Resources, Apr 2022]

Ebf4 Products (1)

mRNA Protein Name
NM_001110513.1 NP_001103983.1 transcription factor COE4

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
12139918 MGI
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
12139918 MGI
enables DNA-binding transcription activator activity, RNA polymerase II-specific IMP
IMP: Inferred from mutant phenotype
12139918 MGI
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IMP
IMP: Inferred from mutant phenotype
12139918 MGI
enables transcription factor binding IPI
IPI: Inferred from physical interaction
12139918 MGI
Biological Process GO Annotation Evidence References Source
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
12139918 MGI
acts upstream of or within regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
12139918 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transcription factor COE4

  • EBF-4

  • OE-4

  • Olf-1/EBF-like 4

  • early B-cell factor 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04127 EBF4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ebf4 NCBI NCBI:57593