2. Gene
  3. ENPP4 - ectonucleotide pyrophosphatase/phosphodiesterase 4 Gene

ENPP4 - ectonucleotide pyrophosphatase/phosphodiesterase 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as NPP4

Gene ID: 22875 | Gene type: protein coding

About ENPP4

Cytogenetic location: 6p21.1 Genomic coordinates (GRCh38): 6:46,129,989-46,146,688 (from NCBI)

This gene has 1 transcript (splice variant), 214 orthologues and 6 paralogues. Ubiquitous expression in bone marrow (RPKM 15.7), brain (RPKM 14.1) and 24 other tissues.

Summary

Enables bis(5'-adenosyl)-triphosphatase activity. Involved in positive regulation of blood coagulation and purine ribonucleoside catabolic process. Located in extracellular exosome and membrane. [provided by Alliance of Genome Resources, Apr 2022]

ENPP4 Products(1)

mRNA Protein Name
NM_014936.5 NP_055751.1 bis(5'-adenosyl)-triphosphatase ENPP4 precursor

ENPP4 Protein Structure

Phosphodiest

Phosphodiest: Type I phosphodiesterase / nucleotide pyrophosphatase (28 - 339)

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  • 453 a.a.
Protein Preferred Names Protein Names

bis(5'-adenosyl)-triphosphatase ENPP4

AP3A hydrolase

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04390 ENPP4 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus ENPP4 RGD RGD:1308689
Canis familiaris ENPP4 VGNC VGNC:49603
Macaca mulatta ENPP4 VGNC VGNC:81066
Mus musculus ENPP4 MGD MGI:2682634
Felis catus ENPP4 VGNC VGNC:102419
Bos taurus ENPP4 VGNC VGNC:49551