Ccm2l - cerebral cavernous malformation 2-like Gene

Mus musculus

Gene ID: 228788 | Gene type: protein coding

About Ccm2l

Summary

Acts upstream of or within several processes, including heart development; negative regulation of homotypic cell-cell adhesion; and positive regulation of Fibroblast Growth Factor production. Is expressed in several structures, including cardiovascular system; immune system; liver; lung; and retina blood vessel. Orthologous to human CCM2L (CCM2 like scaffold protein). [provided by Alliance of Genome Resources, Apr 2022]

Ccm2l Products(2)

mRNA	Protein	Name
NM_001372363.1	NP_001359292.1	cerebral cavernous malformations 2 protein-like isoform 1
NM_145536.3	NP_663511.2	cerebral cavernous malformations 2 protein-like isoform 2

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	22898778	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within cardiac atrium morphogenesis	IGI IGI: Inferred from genetic interaction	22898778	MGI
acts upstream of or within cardiac muscle tissue growth	IGI IGI: Inferred from genetic interaction	22898778	MGI
acts upstream of fibroblast growth factor production	IGI IGI: Inferred from genetic interaction	22898778	MGI
acts upstream of homotypic cell-cell adhesion	IDA IDA: Inferred from direct assay	22898778	MGI
acts upstream of or within negative regulation of homotypic cell-cell adhesion	IDA IDA: Inferred from direct assay	22898778	MGI
acts upstream of or within negative regulation of protein binding	IDA IDA: Inferred from direct assay	22898778	MGI
acts upstream of or within positive regulation of fibroblast growth factor production	IGI IGI: Inferred from genetic interaction	22898778	MGI
acts upstream of or within ventricular trabecula myocardium morphogenesis	IGI IGI: Inferred from genetic interaction	22898778	MGI
acts upstream of or within wound healing	IMP IMP: Inferred from mutant phenotype	22898778	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

cerebral cavernous malformations 2 protein-like

CCM2-like

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02109	CCM2L Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Ccm2l	NCBI	NCBI:140706

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