2. Gene
  3. Osbpl2 - oxysterol binding protein-like 2 Gene

Osbpl2 - oxysterol binding protein-like 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Orp2; ORP-2; C130070J12Rik

Gene ID: 228983 | Gene type: protein coding

About Osbpl2

Summary

Predicted to enable Cholesterol binding activity; lipid transfer activity; and phosphatidylinositol-4,5-bisphosphate binding activity. Predicted to be involved in lipid transport; plasma membrane organization; and protein homotetramerization. Predicted to act upstream of or within lipid transport. Predicted to be extrinsic component of cytoplasmic side of plasma membrane. Predicted to be active in cytosol; intracellular membrane-bounded organelle; and membrane. Predicted to colocalize with lipid droplet. Is expressed in several structures, including central nervous system; genitourinary system; heart; immune system; and lung. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 67. Orthologous to human OSBPL2 (oxysterol binding protein like 2). [provided by Alliance of Genome Resources, Apr 2022]

Osbpl2 Products(1)

mRNA Protein Name
NM_144500.4 NP_653083.2 oxysterol-binding protein-related protein 2
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in regulation of presynaptic cytosolic calcium ion concentration IDA
IDA: Inferred from direct assay
36577376 MGI
Cellular Component GO Annotation Evidence Reference Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
36577376 MGI
is active in presynaptic active zone cytoplasmic component IDA
IDA: Inferred from direct assay
36577376 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

oxysterol-binding protein-related protein 2

OSBP-related protein 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09840 OSBPL2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Osbpl2 NCBI NCBI:9885