Osbpl2 - oxysterol binding protein-like 2 Gene
Also Known as Orp2; ORP-2; C130070J12Rik
Species: Mus musculus
Summary
Predicted to enable Cholesterol binding activity; lipid transfer activity; and phosphatidylinositol-4,5-bisphosphate binding activity. Predicted to be involved in lipid transport; plasma membrane organization; and protein homotetramerization. Predicted to act upstream of or within lipid transport. Predicted to be extrinsic component of cytoplasmic side of plasma membrane. Predicted to be active in cytosol; intracellular membrane-bounded organelle; and membrane. Predicted to colocalize with lipid droplet. Is expressed in several structures, including central nervous system; genitourinary system; heart; immune system; and lung. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 67. Orthologous to human OSBPL2 (oxysterol binding protein like 2). [provided by Alliance of Genome Resources, Apr 2022]
Osbpl2 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_144500.4 | NP_653083.2 | oxysterol-binding protein-related protein 2 |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in regulation of presynaptic cytosolic calcium ion concentration |
IDA
IDA: Inferred from direct assay
|
36577376 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| is active in glutamatergic synapse |
IDA
IDA: Inferred from direct assay
|
36577376 | MGI |
| is active in presynaptic active zone cytoplasmic component |
IDA
IDA: Inferred from direct assay
|
36577376 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
oxysterol-binding protein-related protein 2 |
|