Gatad2b - GATA zinc finger domain containing 2B Gene

Also Known as P66beta; mKIAA1150; C430014D17Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 229542

Summary

Predicted to enable sequence-specific DNA binding activity and zinc ion binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be part of NuRD complex. Is expressed in early conceptus and genitourinary system. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 18. Orthologous to human GATAD2B (GATA zinc finger domain containing 2B). [provided by Alliance of Genome Resources, Apr 2022]

Gatad2b Products (4)

mRNA Protein Name
NM_001379655.1 NP_001366584.1 transcriptional repressor p66-beta isoform a
NM_001379656.1 NP_001366585.1 transcriptional repressor p66-beta isoform a
NM_001379657.1 NP_001366586.1 transcriptional repressor p66-beta isoform b
NM_139304.3 NP_647465.1 transcriptional repressor p66-beta isoform a

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
19321449 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transcriptional repressor p66-beta

  • GATA zinc finger domain-containing protein 2B

  • p66/p68

  • transcription repressor p66 beta component of the MeCP1 complex

  • transcription repressor p66 component of the MeCP1 complex

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P10326 Z-ATAD-FMK Inhibitor / Unkown
HY-RS05297 GATAD2B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gatad2b NCBI NCBI:57459