2. Gene
  3. Gatad2b - GATA zinc finger domain containing 2B Gene

Gatad2b - GATA zinc finger domain containing 2B Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as P66beta; mKIAA1150; C430014D17Rik

Gene ID: 229542 | Gene type: protein coding

About Gatad2b

Summary

Predicted to enable sequence-specific DNA binding activity and zinc ion binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be part of NuRD complex. Is expressed in early conceptus and genitourinary system. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 18. Orthologous to human GATAD2B (GATA zinc finger domain containing 2B). [provided by Alliance of Genome Resources, Apr 2022]

Gatad2b Products(4)

mRNA Protein Name
NM_001379655.1 NP_001366584.1 transcriptional repressor p66-beta isoform a
NM_001379656.1 NP_001366585.1 transcriptional repressor p66-beta isoform a
NM_001379657.1 NP_001366586.1 transcriptional repressor p66-beta isoform b
NM_139304.3 NP_647465.1 transcriptional repressor p66-beta isoform a
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
19321449 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transcriptional repressor p66-beta

GATA zinc finger domain-containing protein 2B

p66/p68

transcription repressor p66 beta component of the MeCP1 complex

transcription repressor p66 component of the MeCP1 complex

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P10326 Z-ATAD-FMK Inhibitor / Unkown
HY-RS05297 GATAD2B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gatad2b NCBI NCBI:57459