2. Gene
  3. Flg2 - filaggrin family member 2 Gene

Flg2 - filaggrin family member 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as EG229574

Gene ID: 229574 | Gene type: protein coding

About Flg2

Summary

Predicted to enable calcium ion binding activity and transition metal ion binding activity. Predicted to be involved in cell adhesion; epidermis morphogenesis; and establishment of skin barrier. Predicted to be located in cytoplasm. Predicted to be active in cornified envelope and keratohyalin granule. Human ortholog(s) of this gene implicated in peeling skin syndrome. Orthologous to human FLG2 (filaggrin 2). [provided by Alliance of Genome Resources, Apr 2022]

Flg2 Products(1)

mRNA Protein Name
NM_001013804.2 NP_001013826.2 filaggrin-2
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
is active in cornified envelope IDA
IDA: Inferred from direct assay
26644517 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

filaggrin-2

intermediate filament-associated protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04919 Fgfr3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04976 FLG2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Flg2 NCBI NCBI:388698