2. Gene
  3. Adamtsl4 - ADAMTS-like 4 Gene

Adamtsl4 - ADAMTS-like 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Tsrc1; ADAMTSL-4

Gene ID: 229595 | Gene type: protein coding

About Adamtsl4

Summary

The protein encoded by this gene is a member of the ADAMTS superfamily of secreted proteins, which contain a metalloprotease domain at the N-terminus and a C-terminal ancillary domain. ADAMTS-like proteins lack protease activity and resemble the ancillary domain of ADAMTS proteins. ADAMTS-like proteins have been implicated in regulation of the extracellular matrix. The encoded protein contains 7 thrombospondin type 1 repeats, a conserved extracellular domain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]

Adamtsl4 Products(4)

mRNA Protein Name
NM_001301705.1 NP_001288634.1 ADAMTS-like protein 4 precursor
NM_144899.3 NP_659148.2 ADAMTS-like protein 4 precursor
NM_001301705.1 NP_001288634.1 ADAMTS-like protein 4 precursor
NM_144899.3 NP_659148.2 ADAMTS-like protein 4 precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within epithelial cell development IMP
IMP: Inferred from mutant phenotype
26405179 MGI
acts upstream of or within extracellular matrix organization IDA
IDA: Inferred from direct assay
18757743 MGI
acts upstream of or within pigment cell development IMP
IMP: Inferred from mutant phenotype
26405179 MGI
Cellular Component GO Annotation Evidence Reference Source
located in extracellular matrix IDA
IDA: Inferred from direct assay
18757743 MGI
located in interstitial matrix IDA
IDA: Inferred from direct assay
18757743 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ADAMTS-like protein 4

thrombospondin repeat containing 1

thrombospondin repeat protein 1

thrombospondin repeat-containing protein 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00313 ADAMTSL4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21787 Thsd4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Adamtsl4 NCBI NCBI:54507