Ahcyl1 - S-adenosylhomocysteine hydrolase-like 1 Gene

Mus musculus

Also known as DCAL; Irbit; Ahcy-rs3; 1110034F20Rik

Gene ID: 229709 | Gene type: protein coding

About Ahcyl1

Summary

Predicted to enable identical protein binding activity. Involved in epithelial fluid transport. Acts upstream of or within several processes, including mRNA polyadenylation; protein export from nucleus; and regulation of ion transport. Located in cytosol and intracellular membrane-bounded organelle. Is expressed in several structures, including alimentary system; integumental system; nervous system; respiratory system; and sensory organ. Orthologous to human AHCYL1 (adenosylhomocysteinase like 1). [provided by Alliance of Genome Resources, Apr 2022]

Ahcyl1 Products(5)

mRNA	Protein	Name
NM_001357110.1	NP_001344039.1	S-adenosylhomocysteine hydrolase-like protein 1 isoform 2
NM_001357111.1	NP_001344040.1	S-adenosylhomocysteine hydrolase-like protein 1 isoform 3
NM_001357112.1	NP_001344041.1	S-adenosylhomocysteine hydrolase-like protein 1 isoform 3
NM_001357113.1	NP_001344042.1	S-adenosylhomocysteine hydrolase-like protein 1 isoform 4
NM_145542.4	NP_663517.2	S-adenosylhomocysteine hydrolase-like protein 1 isoform 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
NOT enables adenosylhomocysteinase activity	IDA IDA: Inferred from direct assay	12525476	MGI
enables enzyme regulator activity	IDA IDA: Inferred from direct assay	19224921	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	16769890	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in epithelial fluid transport	IDA IDA: Inferred from direct assay	23542070	MGI
acts upstream of or within positive regulation of sodium ion transport	IGI IGI: Inferred from genetic interaction	16769890	MGI
acts upstream of or within protein export from nucleus	IDA IDA: Inferred from direct assay	19224921	MGI
acts upstream of or within regulation of mRNA 3'-end processing	IDA IDA: Inferred from direct assay	19224921	MGI
acts upstream of or within regulation of monoatomic anion transport	IGI IGI: Inferred from genetic interaction	19033647	MGI
acts upstream of or within regulation of monoatomic ion transmembrane transporter activity	IGI IGI: Inferred from genetic interaction	16769890	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in cytosol	IDA IDA: Inferred from direct assay	19220705	MGI
located in intracellular membrane-bounded organelle	IDA IDA: Inferred from direct assay	19220705	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

S-adenosylhomocysteine hydrolase-like protein 1

IP3R binding protein released with inositol 1,4,5-trisphosphate	S-adenosyl-L-homocysteine hydrolase 2
S-adenosylhomocysteine hydrolase, related sequence 3	adoHcyase 2
putative adenosylhomocysteinase 2

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00477	AHCYL1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Ahcyl1	NCBI	NCBI:10768

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