Prdm13 - PR domain containing 13 Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 230025

Summary

Enables RNA polymerase II-specific DNA-binding transcription factor binding activity; chromatin binding activity; and Histone Methyltransferase activity. Acts upstream of or within negative regulation of transcription by RNA polymerase II and neurogenesis. Located in nucleus. Is expressed in embryo; future spinal cord; head; and neural tube ventricular layer. Orthologous to human PRDM13 (PR/SET domain 13). [provided by Alliance of Genome Resources, Apr 2022]

Prdm13 Products (1)

mRNA Protein Name
NM_001080771.1 NP_001074240.1 PR domain zinc finger protein 13

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables RNA polymerase II-specific DNA-binding transcription factor binding IDA
IDA: Inferred from direct assay
23639443 MGI
enables RNA polymerase II-specific DNA-binding transcription factor binding IPI
IPI: Inferred from physical interaction
23639443 MGI
enables chromatin binding IDA
IDA: Inferred from direct assay
23639443 MGI
enables histone methyltransferase activity IDA
IDA: Inferred from direct assay
24370451 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
23639443 MGI
Biological Process GO Annotation Evidence References Source
involved in GABAergic neuron differentiation IMP
IMP: Inferred from mutant phenotype
34730112 MGI
involved in hypothalamus cell differentiation IMP
IMP: Inferred from mutant phenotype
34730112 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
23639443 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
23639443 MGI
acts upstream of or within neurogenesis IDA
IDA: Inferred from direct assay
19050759 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
24370451 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

PR domain zinc finger protein 13

  • PR domain-containing protein 13

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11063 PRDM13 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21176 Prdm13 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27693 Prdm13 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Prdm13 NCBI NCBI:59336