Szt2 - SZT2 subunit of KICSTOR complex Gene

Mus musculus

Also known as TIGR; 6430407N22

Gene ID: 230676 | Gene type: protein coding

About Szt2

Summary

This gene encodes a protein associated with low seizure threshold in mice and may contribute to susceptibility to epilepsy. [provided by RefSeq, Aug 2011]

Szt2 Products(1)

mRNA	Protein	Name
NM_198170.4	NP_937813.3	KICSTOR complex protein SZT2

Gene Ontology

Biological Process
Cellular Component

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within central nervous system development	IMP IMP: Inferred from mutant phenotype	19624305	MGI
involved in negative regulation of TORC1 signaling	IMP IMP: Inferred from mutant phenotype	28199306	MGI
acts upstream of or within pigmentation	IMP IMP: Inferred from mutant phenotype	19624305	MGI
acts upstream of or within post-embryonic development	IMP IMP: Inferred from mutant phenotype	19624305	MGI
involved in regulation of superoxide dismutase activity	IMP IMP: Inferred from mutant phenotype	20045724	MGI
involved in response to nutrient levels	IMP IMP: Inferred from mutant phenotype	28199315	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in peroxisome	IDA IDA: Inferred from direct assay	20045724	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

KICSTOR complex protein SZT2

Seizure threshold 2 protein	Transcript increased in glutamate resistance
seaizure threshold 2

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14129	SZT2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Szt2	NCBI	NCBI:23334

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