VWA8 - von Willebrand factor A domain containing 8 Gene

Also Known as P7BP2; KIAA0564

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 23078

About VWA8

Cytogenetic location: 13q14.11 Genomic coordinates (GRCh38): 13:41,566,835-41,961,109 (from NCBI)

This gene has 4 transcripts (splice variants) and 206 orthologues. Ubiquitous expression in kidney (RPKM 6.4), fat (RPKM 4.0) and 25 other tissues.

Summary

Predicted to enable ATP binding activity. Located in mitochondrion and peroxisome. [provided by Alliance of Genome Resources, Apr 2022]

VWA8 Products (2)

mRNA Protein Name
NM_001009814.2 NP_001009814.1 von Willebrand factor A domain-containing protein 8 isoform b precursor
NM_015058.2 NP_055873.1 von Willebrand factor A domain-containing protein 8 isoform a precursor

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
30204880 GOA
Cellular Component GO Annotation Evidence References Source
located in mitochondrion IDA
IDA: Inferred from direct assay
30204880 GOA
located in peroxisome IDA
IDA: Inferred from direct assay
30204880 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

VWA8 Protein Structure

AAA_5

AAA_5: AAA domain (dynein-related subfamily) (105 - 261)

AAA_5

AAA_5: AAA domain (dynein-related subfamily) (442 - 600)

AAA_5

AAA_5: AAA domain (dynein-related subfamily) (776 - 914)

VWA_2

VWA_2: von Willebrand factor type A domain (1717 - 1896)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1500
  • 1800
  • 1905 a.a.
Protein Preferred Names Protein Names

von Willebrand factor A domain-containing protein 8

  • PEX7-binding protein 2

Related Diseases

Diseases Alias
Orofacial Cleft 1

  • OFC1

  • Cleft Lip With Or Without Cleft Palate, Nonsyndromic, 1

  • Orofacial Cleft, Nonsyndromic

  • Ofc

  • Cleft Lip/Palate, Nonsyndromic

  • Orofacial Cleft-1

  • Nonsyndromic Cleft Lip With Or Without Cleft Palate 1

  • Nonsyndromic Cleft Lip Palate

  • Otofaciocervical Syndrome 1
Venezuelan Hemorrhagic Fever

  • Guanarito Hemorrhagic Fever

  • Vehf - [Venezuelan Haemorrhagic Fever]
Migraine With Or Without Aura 1

  • Migraine

  • Migraine With Or Without Aura, Susceptibility To, 1

  • Migraine Disorder

  • Migraine Variant

  • Migraines

  • Migraine Disorders

  • Mgr1

  • Mgau

  • Ma

  • Migraine With Or Without Aura

  • Classic Migraine

  • Common Migraine

  • Disorder, Migraine

  • Headache Migraine

  • Headache Migrainous

  • Migraine Headache

  • Migraine Syndrome

  • Headache Including Migraine

  • Migraine, Susceptibility To
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15731 VWA8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus VWA8 MGD MGI:1919008
Felis catus VWA8 VGNC VGNC:66994
Bos taurus VWA8 VGNC VGNC:36856
Canis familiaris VWA8 VGNC VGNC:48325
Rattus norvegicus VWA8 RGD RGD:1308772
Macaca mulatta VWA8 VGNC VGNC:79773
Others VWA8 NCBI