Igsf21 - immunoglobulin superfamily, member 21 Gene

Mus musculus

Also known as Gm141

Gene ID: 230868 | Gene type: protein coding

About Igsf21

Summary

Involved in synapse maturation. Located in inhibitory synapse and presynaptic membrane. Is anchored component of external side of plasma membrane. Is expressed in nervous system; olfactory epithelium; and retina. Orthologous to human IGSF21 (immunoglobin superfamily member 21). [provided by Alliance of Genome Resources, Apr 2022]

Igsf21 Products(1)

mRNA	Protein	Name
NM_198610.2	NP_941012.1	immunoglobulin superfamily member 21 precursor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	28864826	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in synapse maturation	IMP IMP: Inferred from mutant phenotype	28864826	MGI
involved in trans-synaptic signaling, modulating synaptic transmission	IDA IDA: Inferred from direct assay	28864826	MGI
involved in trans-synaptic signaling, modulating synaptic transmission	IMP IMP: Inferred from mutant phenotype	28864826	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in external side of plasma membrane	IDA IDA: Inferred from direct assay	28864826	MGI
located in inhibitory synapse	IDA IDA: Inferred from direct assay	28864826	MGI
is active in postsynaptic density membrane	IDA IDA: Inferred from direct assay	28864826	MGI
is active in postsynaptic density membrane	IEP IEP: Inferred from expression pattern	28864826	MGI
is active in postsynaptic density membrane	IMP IMP: Inferred from mutant phenotype	28864826	MGI
located in presynaptic membrane	IDA IDA: Inferred from direct assay	28864826	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

immunoglobulin superfamily member 21

immunoglobin superfamily, member 21

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06648	IGSF21 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Igsf21	NCBI	NCBI:84966

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