Agbl5 - ATP/GTP binding protein-like 5 Gene

Also Known as CCP5; 9430057O19Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 231093

Summary

Enables metallocarboxypeptidase activity and tubulin binding activity. Involved in defense response to virus and protein branching point deglutamylation. Located in cytosol and nucleus. Human ortholog(s) of this gene implicated in retinitis pigmentosa 75. Orthologous to human AGBL5 (AGBL Carboxypeptidase 5). [provided by Alliance of Genome Resources, Apr 2022]

Agbl5 Products (14)

mRNA Protein Name
NM_001048192.3 NP_001041657.1 cytosolic carboxypeptidase-like protein 5 isoform 3
NM_001294262.2 NP_001281191.1 cytosolic carboxypeptidase-like protein 5 isoform 6
NM_001374737.2 NP_001361666.1 cytosolic carboxypeptidase-like protein 5 isoform 7
NM_001408078.1 NP_001395007.1 cytosolic carboxypeptidase-like protein 5 isoform 3
NM_001408079.1 NP_001395008.1 cytosolic carboxypeptidase-like protein 5 isoform 8
NM_001408080.1 NP_001395009.1 cytosolic carboxypeptidase-like protein 5 isoform 9
NM_001408081.1 NP_001395010.1 cytosolic carboxypeptidase-like protein 5 isoform 6
NM_001408082.1 NP_001395011.1 cytosolic carboxypeptidase-like protein 5 isoform 10
NM_001408083.1 NP_001395012.1 cytosolic carboxypeptidase-like protein 5 isoform 5
NM_001408084.1 NP_001395013.1 cytosolic carboxypeptidase-like protein 5 isoform 5
NM_001408085.1 NP_001395014.1 cytosolic carboxypeptidase-like protein 5 isoform 11
NM_001408086.1 NP_001395015.1 cytosolic carboxypeptidase-like protein 5 isoform 12
NM_001408087.1 NP_001395016.1 cytosolic carboxypeptidase-like protein 5 isoform 12
NM_174849.4 NP_777274.1 cytosolic carboxypeptidase-like protein 5 isoform 5

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables metallocarboxypeptidase activity IDA
IDA: Inferred from direct assay
20519502 MGI
enables metallocarboxypeptidase activity IMP
IMP: Inferred from mutant phenotype
21074048 MGI
enables tubulin binding IDA
IDA: Inferred from direct assay
21074048 MGI
Biological Process GO Annotation Evidence References Source
involved in C-terminal protein deglutamylation IDA
IDA: Inferred from direct assay
24022482 MGI
involved in defense response to virus IMP
IMP: Inferred from mutant phenotype
26829768 MGI
involved in protein branching point deglutamylation IDA
IDA: Inferred from direct assay
20519502 MGI
involved in protein branching point deglutamylation IMP
IMP: Inferred from mutant phenotype
21074048 MGI
involved in protein deglutamylation IDA
IDA: Inferred from direct assay
20519502 MGI
involved in protein deglutamylation IMP
IMP: Inferred from mutant phenotype
26829768 MGI
involved in protein side chain deglutamylation IMP
IMP: Inferred from mutant phenotype
26829768 MGI
Cellular Component GO Annotation Evidence References Source
located in cytosol IDA
IDA: Inferred from direct assay
17244818 MGI
located in nucleus IDA
IDA: Inferred from direct assay
17244818 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cytosolic carboxypeptidase-like protein 5

  • carboxypeptidase 5, cytosolic

  • protein deglutamylase CCP5

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00443 AGBL5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Agbl5 NCBI NCBI:60509