Cpeb2 - cytoplasmic polyadenylation element binding protein 2 Gene

Also Known as Cpe-bp2; A630055H10Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 231207

Summary

Enables nucleic acid binding activity and ribosome binding activity. Involved in several processes, including cellular response to arsenic-containing substance; cellular response to hypoxia; and negative regulation of cytoplasmic translation. Acts upstream of or within negative regulation of translational elongation. Located in cytoplasm. Part of messenger ribonucleoprotein complex and polysome. Is expressed in central nervous system. Orthologous to human CPEB2 (cytoplasmic polyadenylation element binding protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Cpeb2 Products (5)

mRNA Protein Name
NM_001177379.2 NP_001170850.1 cytoplasmic polyadenylation element-binding protein 2 isoform 2
NM_001368805.1 NP_001355734.1 cytoplasmic polyadenylation element-binding protein 2 isoform 3
NM_001368806.1 NP_001355735.1 cytoplasmic polyadenylation element-binding protein 2 isoform 4
NM_001368807.1 NP_001355736.1 cytoplasmic polyadenylation element-binding protein 2 isoform 5
NM_175937.4 NP_787951.2 cytoplasmic polyadenylation element-binding protein 2 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables mRNA 3'-UTR AU-rich region binding IDA
IDA: Inferred from direct assay
18752464 MGI
enables mRNA regulatory element binding translation repressor activity IDA
IDA: Inferred from direct assay
18752464 MGI
enables poly-pyrimidine tract binding IDA
IDA: Inferred from direct assay
12672660 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
17927953 MGI
enables ribosome binding IDA
IDA: Inferred from direct assay
22157746 MGI
Biological Process GO Annotation Evidence References Source
involved in cellular response to hypoxia IDA
IDA: Inferred from direct assay
18752464 MGI
involved in negative regulation of cytoplasmic translation IDA
IDA: Inferred from direct assay
18752464 MGI
acts upstream of or within negative regulation of translational elongation IGI
IGI: Inferred from genetic interaction
22157746 MGI
involved in regulation of translation at synapse, modulating synaptic transmission IDA
IDA: Inferred from direct assay
29141213 MGI
involved in regulation of translation at synapse, modulating synaptic transmission IMP
IMP: Inferred from mutant phenotype
29141213 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
12672660 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
29141213 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
29141213 MGI
located in ribosome IDA
IDA: Inferred from direct assay
22157746 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cytoplasmic polyadenylation element-binding protein 2

  • CPE-binding protein 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03092 CPEB2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22454 Cpeb2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28977 Cpeb2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cpeb2 NCBI NCBI:132864