Aasdh - aminoadipate-semialdehyde dehydrogenase Gene

Also Known as U26; Acsf4; A830035E16; A230062G08Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 231326

Summary

The gene product is a cytosolic enzyme involved in the production of alpha-aminoadipic acid from alpha-aminoadipic semialdehyde. It is postulated that this enzyme plays a role in lysine metabolism. There is currently debate regarding this enzyme's putative requirement of pyrroloquinoline quinine as an essential cofactor. A related pseudogene has been identified on chromosome 2. [provided by RefSeq, Jan 2010]

Aasdh Products (2)

mRNA Protein Name
NM_001377004.1 NP_001363933.1 beta-alanine-activating enzyme
NM_173765.4 NP_776126.1 beta-alanine-activating enzyme

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within amino acid activation for nonribosomal peptide biosynthetic process IDA
IDA: Inferred from direct assay
24467666 MGI
acts upstream of or within beta-alanine metabolic process IDA
IDA: Inferred from direct assay
24467666 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

beta-alanine-activating enzyme

  • 2-aminoadipic 6-semialdehyde dehydrogenase

  • acyl-CoA synthetase family member 4

  • protein LYS2 homolog

  • putative aminoadipate-semialdehyde dehydrogenase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00031 AASDH Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Aasdh NCBI NCBI:132949