2. Gene
  3. Fras1 - Fraser extracellular matrix complex subunit 1 Gene

Fras1 - Fraser extracellular matrix complex subunit 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as bl; mKIAA1500; E130113P14Rik

Gene ID: 231470 | Gene type: protein coding

About Fras1

Summary

Predicted to enable metal ion binding activity. Predicted to be an extracellular matrix structural constituent. Acts upstream of or within several processes, including animal organ development; embryonic limb morphogenesis; and roof of mouth development. Located in basement membrane. Is expressed in several structures, including alimentary system; body cavity or lining; brain; sensory organ; and skin. Used to study Fraser syndrome and clubfoot. Human ortholog(s) of this gene implicated in Fraser syndrome 1. Orthologous to human FRAS1 (Fraser extracellular matrix complex subunit 1). [provided by Alliance of Genome Resources, Apr 2022]

Fras1 Products(1)

mRNA Protein Name
NM_175473.3 NP_780682.3 extracellular matrix organizing protein FRAS1 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
14730302 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within embryonic limb morphogenesis IMP
IMP: Inferred from mutant phenotype
23469164 MGI
acts upstream of or within metanephros morphogenesis IMP
IMP: Inferred from mutant phenotype
23469164 MGI
acts upstream of or within morphogenesis of an epithelium IMP
IMP: Inferred from mutant phenotype
15838507 MGI
acts upstream of or within protein transport IMP
IMP: Inferred from mutant phenotype
17596926 MGI
acts upstream of or within roof of mouth development IMP
IMP: Inferred from mutant phenotype
23469164 MGI
acts upstream of or within skin development IMP
IMP: Inferred from mutant phenotype
17596926 MGI
Cellular Component GO Annotation Evidence Reference Source
located in basement membrane IDA
IDA: Inferred from direct assay
15345741 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

extracellular matrix organizing protein FRAS1

extracellular matrix protein FRAS1

Fraser syndrome 1 homolog

Fraser syndrome 1 protein

blebbed

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-17663 KMR-206 98.86% Unkown
HY-RS05089 FRAS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P990417 Anti-FOLR1/FRA Antibody / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fras1 NCBI NCBI:80144