Ap5z1 - adaptor-related protein complex 5, zeta 1 subunit Gene

Also Known as C330006K01Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 231855

Summary

Predicted to be involved in double-strand break repair via homologous recombination and endosomal transport. Predicted to act upstream of or within DNA repair and protein transport. Predicted to be located in cytoplasm and nuclear speck. Predicted to be part of AP-5 adaptor complex. Used to study hereditary spastic paraplegia 48. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia and hereditary spastic paraplegia 48. Orthologous to human AP5Z1 (adaptor related protein complex 5 subunit zeta 1). [provided by Alliance of Genome Resources, Apr 2022]

Ap5z1 Products (1)

mRNA Protein Name
NM_172725.2 NP_766313.2 AP-5 complex subunit zeta-1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
37871017 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within Golgi organization IMP
IMP: Inferred from mutant phenotype
30930081 MGI
acts upstream of or within autophagosome assembly IMP
IMP: Inferred from mutant phenotype
30930081 MGI
acts upstream of or within autophagy IMP
IMP: Inferred from mutant phenotype
30930081 MGI
acts upstream of or within axon development IMP
IMP: Inferred from mutant phenotype
30930081 MGI
acts upstream of or within gene expression IMP
IMP: Inferred from mutant phenotype
37871017 MGI
acts upstream of or within intracellular protein transport IMP
IMP: Inferred from mutant phenotype
37871017 MGI
acts upstream of or within late endosome to Golgi transport IMP
IMP: Inferred from mutant phenotype
30930081 MGI
acts upstream of or within lysosomal protein catabolic process IMP
IMP: Inferred from mutant phenotype
30930081 MGI
acts upstream of or within lysosome organization IMP
IMP: Inferred from mutant phenotype
37871017 MGI
Cellular Component GO Annotation Evidence References Source
is active in lysosome IMP
IMP: Inferred from mutant phenotype
37871017 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

AP-5 complex subunit zeta-1

  • adapter-related protein complex 5 zeta subunit

  • adaptor-related protein complex 5 zeta subunit

  • zeta5

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00800 AP5Z1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ap5z1 NCBI NCBI:9907