ZC3H4 - zinc finger CCCH-type containing 4 Gene

Also Known as C19orf7

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 23211

About ZC3H4

Cytogenetic location: 19q13.32 Genomic coordinates (GRCh38): 19:47,064,187-47,113,776 (from NCBI)

This gene has 5 transcripts (splice variants), 199 orthologues and 2 paralogues. Ubiquitous expression in spleen (RPKM 3.8), ovary (RPKM 2.9) and 25 other tissues.

Summary

This gene encodes a member of a family of CCCH (C-x8-C-x5-C-x3-H type) zinc finger domain-containing proteins. These zinc finger domains, which coordinate zinc finger binding and are characterized by three cysteine residues and one histidine residue, are nucleic acid-binding. Other family members are known to function in post-transcriptional regulation. [provided by RefSeq, Aug 2011]

ZC3H4 Products (1)

mRNA Protein Name
NM_015168.2 NP_055983.1 zinc finger CCCH domain-containing protein 4

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables RNA binding IDA
IDA: Inferred from direct assay
33913806 GOA
enables promoter-specific chromatin binding IDA
IDA: Inferred from direct assay
33913806 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
33913806 GOA
Biological Process GO Annotation Evidence References Source
involved in lncRNA catabolic process IDA
IDA: Inferred from direct assay
33913806 GOA
involved in negative regulation of DNA-templated transcription, elongation IDA
IDA: Inferred from direct assay
33913806 GOA
involved in negative regulation of lncRNA transcription IDA
IDA: Inferred from direct assay
33913806 GOA
involved in nuclear RNA surveillance IDA
IDA: Inferred from direct assay
33913806 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZC3H4 Protein Structure

zf-CCCH

zf-CCCH: Zinc finger C-x8-C-x5-C-x3-H type (and similar) (420 - 444)

  • 0
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  • 1200
  • 1303 a.a.
Protein Preferred Names Protein Names

zinc finger CCCH domain-containing protein 4

Related Diseases

Diseases Alias
Pulmonary Talcosis

  • Pneumoconiosis Due To Talc

  • Talc Pneumoconiosis

  • Talcosis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15993 ZC3H4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris ZC3H4 VGNC VGNC:48559
Felis catus ZC3H4 VGNC VGNC:67186
Mus musculus ZC3H4 MGD MGI:2682314
Rattus norvegicus ZC3H4 RGD RGD:1596943
Bos taurus ZC3H4 VGNC VGNC:37106
Macaca mulatta ZC3H4 VGNC VGNC:79094
Others ZC3H4 NCBI