PRRC2C - proline rich coiled-coil 2C Gene

Also Known as XTP2; BAT2D1; BAT2L2; BAT2-iso

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 23215

About PRRC2C

Cytogenetic location: 1q24.3 Genomic coordinates (GRCh38): 1:171,485,530-171,593,511 (from NCBI)

This gene has 13 transcripts (splice variants), 206 orthologues and 2 paralogues. Ubiquitous expression in bone marrow (RPKM 24.0), lymph node (RPKM 17.9) and 25 other tissues.

Summary

Enables protein C-terminus binding activity. Involved in stress granule assembly. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

PRRC2C Products (2)

mRNA Protein Name
NM_001387844.1 NP_001374773.1 protein PRRC2C isoform 2
NM_015172.4 NP_055987.2 protein PRRC2C isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
17577209 GOA
Biological Process GO Annotation Evidence References Source
involved in stress granule assembly IMP
IMP: Inferred from mutant phenotype
29395067 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PRRC2C Protein Structure

BAT2_N

BAT2_N: BAT2 N-terminus (1 - 161)

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  • 2817 a.a.
Protein Preferred Names Protein Names

protein PRRC2C

  • BAT2 domain containing 1

Related Diseases

Diseases Alias
Spastic Paraplegia 10, Autosomal Dominant

  • SPG10

  • Hereditary Spastic Paraplegia 10

  • Autosomal Dominant Spastic Paraplegia Type 10

  • Spastic Paraplegia 10

  • Spastic Paraplegia 10 With Or Without Peripheral Neuropathy

  • Autosomal Dominant Spastic Paraplegia 10

  • Autosomal Dominant Spastic Paraplegia

  • Spastic Paraplegia, Autosomal Dominant

  • Paraplegia, Spastic, Autosomal Dominant, Type 10
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11238 PRRC2C Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus PRRC2C MGD MGI:1913754
Bos taurus PRRC2C VGNC VGNC:33406
Felis catus PRRC2C VGNC VGNC:64391
Macaca mulatta PRRC2C VGNC VGNC:76311
Canis familiaris PRRC2C VGNC VGNC:45054
Rattus norvegicus PRRC2C RGD RGD:1566064
Others PRRC2C NCBI