Frmd4b - FERM domain containing 4B Gene

Also Known as GRSP1; GOBLIN; 6030440G05Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 232288

Summary

Acts upstream of or within establishment of epithelial cell polarity. Located in several cellular components, including adherens junction; bicellular tight junction; and ruffle. Is expressed in several structures, including gallbladder; genitourinary system; gut; nervous system; and vascular system. Orthologous to human FRMD4B (FERM domain containing 4B). [provided by Alliance of Genome Resources, Apr 2022]

Frmd4b Products (3)

mRNA Protein Name
NM_001346637.1 NP_001333566.1 FERM domain-containing protein 4B isoform 1
NM_001346639.1 NP_001333568.1 FERM domain-containing protein 4B isoform 2
NM_145148.2 NP_660130.2 FERM domain-containing protein 4B isoform 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
11445584 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within establishment of epithelial cell polarity IGI
IGI: Inferred from genetic interaction
20080746 MGI
Cellular Component GO Annotation Evidence References Source
located in adherens junction IDA
IDA: Inferred from direct assay
20080746 MGI
located in bicellular tight junction IDA
IDA: Inferred from direct assay
20080746 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
11445584 MGI
located in ruffle IPI
IPI: Inferred from physical interaction
11445584 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

FERM domain-containing protein 4B

  • GRP1 binding protein GRSP1

  • golgi-associated band 4.1-like protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05102 FRMD4B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Frmd4b NCBI NCBI:23150