Ankrd26 - ankyrin repeat domain 26 Gene

Also Known as mKIAA1074; 5730521P14Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 232339

Summary

Involved in negative regulation of fat cell differentiation. Acts upstream of or within several processes, including glucose homeostasis; negative regulation of organ growth; and negative regulation of signal transduction. Located in actin Cytoskeleton. Used to study obesity. Human ortholog(s) of this gene implicated in thrombocytopenia. Orthologous to several human genes including ANKRD26 (ankyrin repeat domain 26). [provided by Alliance of Genome Resources, Apr 2022]

Ankrd26 Products (1)

mRNA Protein Name
NM_001081112.2 NP_001074581.1 ankyrin repeat domain-containing protein 26

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
21689717 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of ERK1 and ERK2 cascade IMP
IMP: Inferred from mutant phenotype
21669876 MGI
acts upstream of fat cell differentiation IMP
IMP: Inferred from mutant phenotype
21669876 MGI
acts upstream of or within glucose homeostasis IMP
IMP: Inferred from mutant phenotype
21842266 MGI
acts upstream of insulin receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
21842266 MGI
acts upstream of or within negative regulation of ERK1 and ERK2 cascade IMP
IMP: Inferred from mutant phenotype
21669876 MGI
acts upstream of or within negative regulation of fat cell differentiation IMP
IMP: Inferred from mutant phenotype
21669876 MGI
involved in negative regulation of fat cell differentiation IMP
IMP: Inferred from mutant phenotype
22666460 MGI
acts upstream of or within negative regulation of insulin receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
21842266 MGI
acts upstream of or within negative regulation of multicellular organism growth IMP
IMP: Inferred from mutant phenotype
18162531 MGI
acts upstream of or within negative regulation of organ growth IMP
IMP: Inferred from mutant phenotype
18162531 MGI
acts upstream of organ growth IMP
IMP: Inferred from mutant phenotype
18162531 MGI
acts upstream of or within regulation of fatty acid metabolic process IMP
IMP: Inferred from mutant phenotype
18162531 MGI
acts upstream of or within regulation of feeding behavior IMP
IMP: Inferred from mutant phenotype
18162531 MGI
acts upstream of or within regulation of lipid metabolic process IMP
IMP: Inferred from mutant phenotype
18162531 MGI
Cellular Component GO Annotation Evidence References Source
located in actin cytoskeleton IDA
IDA: Inferred from direct assay
18162531 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ankyrin repeat domain-containing protein 26

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00719 ANKRD26 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ankrd26 NCBI NCBI:22852